About UsDepartmentsInternational Symposium on Traditional Medicine in ToyamaMuseum of Materia Medica

Division of Pharmacognosy, Department of Medicinal Resources


TEL:076-434-7601; Fax:076-434-5064
[English] http://www.inm.u-toyama.ac.jp/en/departments/01_pharmacognosy.html
[Japanese] http://www.inm.u-toyama.ac.jp/jp/departments/01_pharmacognosy.html
[Website of the Division] http://www.inm.u-toyama.ac.jp/pharmacognosy/index-e.html

Professor Katsuko Komatsu
Professor
Katsuko Komatsu, Ph.D
Associate Professor Kazufumi Toume
Associate Professor
Kazufumi Toume, Ph.D

Assistant Professor Shu Zhu
Assistant Professor
Shu Zhu, Ph.D.

Research Outline

Aim to develop a strategy for the sustainable use of herbal drug resources, comprehensive studies have been conducted in the division of Pharmacognosy, including field investigation on medicinal plants and traditional medicines, molecular systematic, pharmacognostical, chemical and pharmacological analyses on various crude drugs. The contents of researches are as follows.



1)

Field investigation on herbal drug resources around Asian countries and analysis on diversity of the medicinal plants.

2)

Authentication and quality evaluation on various herbal drugs for the purpose of selecting proper species for cultivation.

3)

Analyzing genetic polymorphisms of medicinal plants and developing DNA microarray for identification of herbal drugs.

4)

Chemometric profiling of multiple components in crude drugs and Kampo formula using NMR, LC-MS.

5)

Search and structure elucidation of bioactive compounds from traditional medicines.

6)

Constructing and expanding the database on natural medicines (ETHMED, TradMPD, Shoruihonzo DB).

   
【keywords】
  Traditional medicines, Field investigation, Quality evaluation, Genetic polymorphisms, Cultivation of medicinal plants, Chemometric profiling, Standardization, Sustainability, Bioactive natural products, Biodiversity of medicinal plants

chart

MS/MS similarity network with an input of six reference saponins (yellow nodes) uncover an ion-cluster of triterpene saponins from the water extracts of Eleutherococcus senticosus leaves (ESL). Moreover, the distribution features of 106 triterpene saponins in ESL samples collected from different areas are investigated.