2017 2016 2015 2014 2013 2012 2011 2010 2009


1) Hayashi S., Hamada T., Zinsou D. G. A., Oshiro M., Itoi K., Yamamoto T., Kadowaki M.: PI3K p85 Subunit-deficient Macrophages Protect Mice from Acute Colitis due to the Enhancement of IL-10 Production. Sci Rep., 7: 6187, 2017. doi: 10.1038/s41598-017-06464-w. [Abstract]
2) Kazuma K., Ando K., Nihei K. I., Wang X., Rangel M., Franzolin M. R., Mori-Yasumoto K., Sekita S., Kadowaki M., Satake M., Konno K.: Peptidomic Analysis of the Venom of the Solitary Bee Xylocopa Appendiculata Circumvolans. J. Venom. Anim. Toxins Incl. Trop. Dis., 23: 40, 2017. doi: 10.1186/s40409-017-0130-y. [Abstract]


1) Yamamoto T., Fujiwara K., Tsubota Y., Kageyama-Yahara N., Hayashi S., Kadowaki M.: Induction of Regulatory T Cells as a Novel Mechanism Underlying the Therapeutic Action of Kakkonto, a Traditional Japanese Herbal Medicine, in a Murine Food Allergy Model. Int. Arch. Allergy Immunol., 169: 146-156, 2016. doi: 10.1159/000445433. [Abstract]
2) Shi Y. H., Zhu S., Tamura T., Kadowaki M., Wang Z., Yoshimatsu K., Komatsu K.: Chemical Constituents with Anti-allergic Activity from the Root of Edulis Superba, a Horticultural Cultivar of Paeonia Lactiflora. J. Nat. Med., 70: 234-240, 2016. doi: 10.1007/s11418-016-0966-4. [Abstract]
3) Yamamoto H., Maeda K., Arima H., Sonoda H., Shimizu T., Mekata E., Kaida S., Yamaguchi T., Murata S., Miura K., Kadowaki M., Tani M.: Perioperative Adiponectin Measurement is Useful for Prediction of Postoperative Infection in Patients with Colorectal Cancer. Ann. Surg. Oncol., 23 (Suppl 4): 540-545, 2016. doi: 10.1159/000445433. [Abstract]
4) Takeuchi K., Endoh T., Hayashi S., Aihara T.: Activation of Muscarinic Acetylcholine Receptor Subtype 4 is Essential for Cholinergic Stimulation of Gastric Acid Secretion: Relation to D cell/Somatostatin. Front. Pharmacol., 7: 278, 2016. doi: 10.3389/fphar.2016.00278. [Abstract]
5) Yamada-Nomoto K., Yoshino O., Akiyama I., Ushijima A., Ono Y., Shima T., Nakashima A., Hayashi S., Kadowaki M., Osuga Y., Saito S.: Alpha-7 Nicotinic Acetylcholine Receptor (nAChR) Agonist Inhibits the Development of Endometriosis by Regulating Inflammation. Am. J. Reprod. Immunol., 76: 491-498, 2016. doi: 10.1111/aji.12592. [Abstract]
6) Nagata Y., Yamamoto T., Hayashi M., Hayashi S., Kadowaki M.: Improvement of Therapeutic Efficacy of Oral Immunotherapy in Combination with Regulatory T Cell-Inducer Kakkonto in a Murine Food Allergy Model. PLoS One, 12: e0170577, 2017. doi: 10.1371/journal.pone.0170577. [Abstract]


1) Kato S., Hayashi S., Kitahara Y., Nagasawa K., Aono H., Shibata J., Utsumi D., Amagase K., Kadowaki M.: Saireito (TJ-114), a Japanese traditional herbal medicine, reduces 5-fluorouracil-induced intestinal mucositis in mice by inhibiting cytokine-mediated apoptosis in intestinal crypt cells. PLoS One. 10: e0116213, 2015. [Abstract]
2) Takeuchi K., Ise F., Takahashi K., Aihara E., Hayashi S.: H2S-induced HCO3- secretion in the rat stomach–involvement of nitric oxide, prostaglandins, and capsaicin-sensitive sensory neurons. Nitric Oxide. 46: 157-164, 2015. [Abstract]
3) Takeuchi K., Kita K., Takahashi K., Aihara E., Hayashi S.: Muscarinic acetylcholine receptor subtype 4 is essential for cholinergic stimulation of duodenal bicarbonate secretion in mice– relationship to D cell/somatostatin. Journal of Physiology and Pharmacology. 66: 391-401, 2015. [Abstract]


1) Yamamoto T., Kodama T., Lee J., Utsunomiya N., Hayashi S., Sakamoto H., Kuramoto H., Kadowaki M.: Anti-allergic role of cholinergic neuronal pathway via α7 nicotinic ACh receptors on mucosal mast cells in a murine food allergy model. PLoS One. 9: e85888, 2014. [Abstract]
2) Li P., Zhao QL., Wu LH., Jawaid P., Jiao YF., Kadowaki M., Kondo T.: Isofraxidin, a potent reactive oxygen species (ROS) scavenger, protects human leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in p53-independent manner. Apoptosis. 19: 1043-1053, 2014. [Abstract]
3) Hayashi S., Kurata N., Yamaguchi A., Amagase K., Takeuchi K.: Lubiprostone prevents nonsteroidal anti-inflammatory drug-induced small intestinal damage by suppressing the expression of inflammatory mediators via EP4 receptors. Journal of Pharmacology and Experimental Therapeutics. 349: 470-479, 2014. [Abstract]
4) Zaidi SF., Kim JH., Tomoe Y., Usmanghani K, Kadowaki M.: Effect of Pakistani medicinal plants on IgE/antigen- and ionophore-induced mucosal mast cells degranulation. Pakistan Journal of Pharmaceutical Sciences. 27: 1041-1048, 2014. [Abstract]
5) Kim JH., Yamamoto T., Lee J., Yashiro T., Hamada T., Hayashi S., Kadowaki M.: CGRP, a neurotransmitter of enteric sensory neurons, contributes to the development of food allergy due to the augmentation of microtubule reorganization in mucosal mast cells. Biomedical Research. 35: 285-293, 2014. [Abstract]
6) Wu LH., Li P., Zhao QL., Piao JL., Jiao YF., Kadowaki M., Kondo T.: Arbutin, an intracellular hydroxyl radical scavenger, protects radiation-induced apoptosis in human lymphoma U937 cells. Apoptosis. 19: 1654-1663, 2014. [Abstract]
7) Hayashi S., Hamada T., Zaidi SF., Oshiro M., Lee J., Yamamoto T., Ishii Y., Sasahara M., Kadowaki M.: Nicotine suppresses acute colitis and colonic tumorigenesis associated with chronic colitis in mice. Americal Journal of Physiology Gastrointestinal and Liver Physiology. 307: G968-978, 2014. [Abstract]
8) Wang X., Hayashi S., Umezaki M., Yamamoto T., Kageyama-Yahara N., Kondo T., Kadowaki M.: Shikonin, a constituent of Lithospermum erythrorhizon exhibits anti-allergic effects by suppressing orphan nuclear receptor Nr4a family gene expression as a new prototype of calcineurin inhibitors in mast cells. Chemico-Biological Interactions. 224: 117-127, 2014. [Abstract]


1) Piao J.L., Cui Z.G., Furusawa Y., Ahmed K., Rehman M.U., Tabuchi Y., Kadowaki M., Kondo T.: The molecular mechanisms and gene expression profiling for shikonin-induced apoptotic and necroptotic cell death in U937 cells. Chemico-Biological Interactions. 205: 119-127, 2013. [Abstract]
2) Oda S., Uchida K., Wang X., Lee J., Shimada Y., Tominaga M., Kadowaki M.: TRPM2 contributes to antigen-stimulated Ca²+ influx in mucosal mast cells. Pflügers Archiv-European Journal of Physiology. 465: 1023-1030, 2013. [Abstract]
3) Lee J., Yamamoto T., Hayashi S., Kuramoto H., Kadowaki M.: Enhancement of CGRP sensory afferent innervation in the gut during the development of food allergy in an experimental murine model. Biochemical and Biophysical Research Communications. 430: 895-900, 2013. [Abstract]
4) Kuramoto H., Kadowaki M., Yoshida N.: Morphological demonstration of a vagal inhibitory pathway to the lower esophageal sphincter via nitrergic neurons in the rat esophagus. Neurogastroenterology & Motility. 25: 485-494, 2013. [Abstract]
5) Hayashi S., Kurata N., Kitahirachi E., Nishimura Y., Amagase K., Yano T., Takeuchi K.: Cinacalcet, a calcimimetic, prevents nonsteroidal antiinflammatory drug-induced small intestinal damage in rats. Journal of Physiology and Pharmacology. 64: 453-463, 2013. [Abstract]


1) Emam H., Zhao QL., Furusawa Y., Refaat A., Ahmed K., Kadowaki M., Kondo T.: Apoptotic cell death by the novel natural compound, cinobufotalin. Chemico-Biological Interactions. 199:154-60, 2012. [Abstract]
2) Wang X., Kageyama-Yahara N., Hayashi S., Yamamoto T., Kadowaki M.: Sphingosine kinase-1-dependent and -independent inhibitory effects of zanthoxyli fructus to attenuate the activation of mucosal mast cells and ameliorate food allergies in mice. Evidence-Based Complementary and Alternative Medicine. 862743, 2012. [Abstract]
3) Yamamoto T., Tsubota Y., Kodama T., Kageyama-Yahara., Kadowaki M.: Oral tolerance induced by transfer of food antigens via breast milk of allergic mothers prevents offspring from developing allergic symptoms in a mouse food allergy model. Clinical & Developmental Immunology. 721085, 2012. [Abstract]
4) Ahmed K., Furusawa Y., Tabuchi Y., Emam HF., Piao JL., Hassan MA., Yamamoto T., Kondo T., Kadowaki M.: Chemical inducers of heat shock proteins derived from medicinal plants and cytoprotective genes response. International Journal of Hyperthermia 28:1-8, 2012. [Abstract]
5) Lee J., Yamamoto T., Kuramoto H., Kadowaki M.: TRPV1 expressing extrinsic primary sensory neurons play a protective role in mouse oxazolone-induced colitis. Autonomic Neuroscience 166:72-76, 2012. [Abstract]
6) Zaidi SF., Muhammad JS., Shahryar S., Usmanghani K., Gilani AH., Jafri W., Sugiyama T.: Anti-inflammatory and cytoprotective effects of selected Pakistani medicinal plants in Helicobacter pylori-infected gastric epithelial cells. Journal of Ethnopharmacology, 141:403-410, 2012. [Abstract]


1) Kageyama-Yahara N., Wang X., Katagiri T., Wang P., Yamamoto T., Tominaga M., Kadowaki M.: Suppression of phospholipase Cγ1 phosphorylation by cinnamaldehyde inhibits antigen-induced extracellular calcium influx and degranulation in mucosal mast cells. Biochemical and Biophysical Research Communications. 416:283-288, 2011. [Abstract]
2) Rangel M., Cabrera MP., Kazuma K., Ando K., Wang X., Kato M., Nihei K., Hirata IY., Cross TJ., Garcia AN., Faquim-Mauro EL., Franzolin MR., Fuchino H., Mori-Yasumoto K., Sekita S., Kadowaki M., Satake M., Konno K.: Chemical and biological characterization of four new linear cationic α-helical peptides from the venoms of two solitary eumenine wasps. Toxicon 57:1081-1092, 2011. [Abstract]
3) Kageyama-Yahara N., Suehiro Y., Yamamoto T., Kadowaki M.: Rab5a regulates surface expression of FcεRI and functional activation in mast cells. Biological & Pharmaceutical Bulletin 34:760-763, 2011. [Abstract]
4) Takasuka H., Hayashi S., Koyama M., Yasuda M., Aihara E., Amagase K., Takeuchi K.: Carbon monoxide involved in modulating HCO3- secretion in rat duodenum. Journal of Pharmacology and Experimental Therapeutics 377:293-300, 2011. [Abstract]
5) Ise F., Takasuka H., Hayashi S., Takahashi K., Koyama M., Aihara E., Takeuchi K.: Stimulation of duodenal HCO3- secretion by hydrogen sulphide in rats: relation to prostaglandins, nitric oxide and sensory neurones. Acta Physiologica 201:117-126, 2011. [Abstract]


1) Kageyama-Yahara N., Wang P., Wang X., Yamamoto T., Kadowaki M.: The inhibitory effect of ergosterol, a bioactive constituent of a traditional Japanese herbal medicine saireito on the activity of mucosal-type mast cells. Biological & Pharmaceutical Bulletin 33:142-145, 2010. [Abstract]
2) Kageyama-Yahara N., Suehiro Y., Maeda F., Kageyama S., Fukuoka J., Katagiri T., Yamamoto T., Kadowaki M.: Pentagalloylglucose down-regulates mast cell surface FcepsilonRI expression in vitro and in vivo. FEBS Letter. 584:111-118, 2010. [Abstract]
3) Amagase K., Nakamura E., Endo T., Hayashi S., Hasumura M., Uneyama H., Torii K., Takeuchi K.: New frontiers in gut nutrient sensor research: prophylactic effect of glutamine against Helicobacter pylori-induced gastric diseases in Mongolian gerbils. Journal of Pharmacological Sciences 112: 25-32, 2010. [Abstract]


1) Zaidi S. F., Yamamoto T., Refaat A., Ahmed K., Sakurai H., Saiki I., Kondo T., Usmanghani K., Kadowaki M., Sugiyama T. : Modulation of activation-induced cytidine deaminase by curcumin in Helicobacter pylori-infected gastric epithelial cells. Helicobacter 14: 588-595, 2009.[Abstract]
2) Zaidi S. F., Ahmed K., Yamamoto T., Kondo T., Usmanghani K., Kadowaki M., Sugiyama T.: Effect of resveratrol on helicobacter pylori-induced interleukin-8 secretion, reactive oxygen species generation and morphological changes in human gastric epithelial cells. Biological & Pharmaceutical Bulletin 32: 1931-1935, 2009.[Abstract]
3) Watanabe T., Yamamoto T., Yoshida M., Fujiwara K., Kageyama-Yahara N., Kuramoto H., Shimada Y., Kadowaki M.: The Traditional Herbal Medicine Saireito Exerts Its Inhibitory Effect on Murine Oxazolone-Induced Colitis via the Induction of Th1-Polarized Immune Responses in the Mucosal Immune System of the Colon.[Abstract]
4) Zaidi S. F., Yoshida I., Butt F., Yusuf M. A., Usmanghani K., Kadowaki M., Sugiyama T.: Potent bactericidal constituents from Mallotus philippinensis against clarithromycin and metronidazole resistant strains of Japanese and Pakistani Helicobacter pylori. Biological & Pharmaceutical Bulletin 32: 631-636, 2009.[Abstract]
5) Zaidi S. F., Yamada K., Kadowaki M., Usmanghani K., Sugiyama T.: Bactericidal activity of medicinal plants, employed for the treatment of gastrointestinal ailments, against Helicobacter pylori. Journal of Ethnopharmacology 121: 286-291, 2009.[Abstract]
6) Kawabata F., Inoue N., Masamoto Y., Matsumura S., Kimura W., Kadowaki M., Higashi T., Tominaga M., Inoue K., Fushiki T.: Non-pungent capsaicin analogs (capsinoids) increase metabolic rate and enhance thermogenesis via gastrointestinal TRPV1 in mice. Bioscience, Biotechnology, and Biochemistry, 73: 2690-2697, 2009.[Abstract]