病態生化学分野
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研究業績

≪ 前年 2007年 翌年 ≫

Books and Reviews

1) Sakurai H., and Saiki I.:
Anti-tumor activity of Juzentaihoto by modulating immune system.
The23rd annual meeting of medical and Pharmaceutical Society for WAKAN-YAKU (ed.),
Recent Advances in Wakanyaku (Japanese-Chinese traditional medicine) research in Japan and China. Funahashi Printing & Co. Ltd., Gifu, 2007, pp71-97.

2) Koizumi K., Hojo S., Akashi T., Yasumoto K., and Saiki I.:
Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response

Cancer Sci., 98:1652-1658, 2007. [Abstract]
3) 櫻井宏明:
TAK1活性化の分子機構と生理機能の新展開
生化学, 79:883-887, 2007. [Abstract]
4) 済木育夫:
薬学教育と漢方に関する最近の動向など
漢方と最新治療, 16:117-120, 2007.
 

Original Papers

1) Matsuo M., Sakurai H., Koizumi K., and Saiki I.:
Curcumin inhibits the formation of capillary-like tubes by rat lymphatic endothelial cells.

Cancer Lett., 251: 288-295, 2007. [Abstract]
2) Tsunoda S., Nakamura T., Sakurai H., and Saiki I.:
FGF-2-induced host stroma reaction during the initial tumor growth promotes progression of mouse melanoma via VEGFA-dependent neovascularization.

Cancer Sci., 98: 541-548, 2007. [Abstract]
3) Chuethong J., Oda K., Sakurai H., Saiki I., and Leelamanit W.:
Cochinin B, a novel ribosome-inactivating protein from the seeds of Momordica cochinchinensis.

Biol. Pharm. Bull., 30: 428-432, 2007. [Abstract]
4) Koizumi K., Kozawa Y., Ohashi Y., Nakamura E.S., Aozuka Y., Sakurai H., Ichiki K., Doki Y., Misaki T., and Saiki I.:
CCL21 promotes the migration and adhesion of highly metastatic human non-small cell lung cancer Lu-99 in vitro.
Oncol. Rep., 17:1511-1516, 2007. [Abstract]
5) Shambharkar P.B., Blonska M., Pappu B.P., You Y., Sakurai H., Darnay B., and Lin X.:
Phosphorylation and ubiquitination of the IκB kinase complex by two distinct signaling pathways.

EMBO J., 26: 1794-1805, 2007. [Abstract]
6) Singhirunnusorn P., Ueno Y., Matsuo M., Suzuki S., Saiki I., and Sakurai H.:
Transient suppression of ligand-mediated activation of epidermal growth factor receptor by tumor necrosis factor-α through the TAK1-p38 pathway.

J. Biol. Chem., 282: 12698.12706, 2007. [Abstract]
7) Hojo S., Koizumi K., Tsuneyama K., Arita Y., Cui Z., Shinohara K., Minami T., Hashimoto I., Nakayama T., Sakurai H., Takano Y., Yoshie O., Tsukada K., and Saiki I.:
High level expression of chemokine CXCL16 by tumor cells correlated with a good prognosis and increased tumor-infiltrating lymphocytes in colorectal cancer.

Cancer Res., 67: 4725-4731, 2007. [Abstract]
8) Igarashi Y., Trujillo M.E., Mart?nez-Molina E., Yanase S., Miyanaga S., Obata T., Sakurai H., Saiki S., Fujita T., and Furumai T.:
Antitumor anthraquinones from an endophytic actinomycete Micromonospora lupini sp. nov.

Bioorg. Med. Chem. Lett., 17: 3702-3705, 2007. [Abstract]
9) Matsuo M., Yamada S., Koizumi K., Sakurai H., and Saiki I.:
Tumour-derived fibroblast growth factor-2 exerts lymphangiogenic effects through Akt/mTOR/p70S6kinase pathway in rat lymphatic endothelial cells.

Eur. J. Cancer, 43: 1748-1754, 2007. [Abstract]
10) Kammasud N., Grierson D., Tsunoda S., Sakurai H., Saiki I., and Vajragupta O.:
Novel inhibitor for fibroblast growth factor receptor tyrosine kinase.

Bioorg. Med. Chem. Lett., 17: 4812-4818, 2007. [Abstract]
11) Ogawa K., Kojima T., Matsumoto C., Kamegai S., Oyama T., Shibagaki Y., Kawasaki T., Fujinaga H., Takahashi K., Hikiami H., Goto H., Kiga C., Koizumi K., Sakurai H., Muramoto H., Shimada Y., Yamamoto M., Terasawa K., Takeda S., and Saiki I.:
Identification of a predictive biomarker for the beneficial effect of a Kampo (Japanese traditional) medicine keishibukuryogan in rheumatoid arthritis patients.

Clin. Biochem., 40: 1113-1121, 2007. [Abstract]
12) Suzuki S., Singhirunnusorn P., Mori A., Yamaoka S., Kitajima I., Saiki I., and Sakurai H.:
Constitutive activation of TAK1 by HTLV-1 Tax-dependent overexpression of TAB2 induces activation of JNK-ATF2, but not IKK-NF-κB.

J. Biol. Chem., 282: 25177-25181, 2007. [Abstract]
13) Nozaki K., Goto H., Nakagawa T., Hikiami H., Koizumi K., Shibahara N., and Shimada Y.:
Effects of keishibukuryogan on vascular function in adjuvant-induced arthritis rats.

Biol. Pharm. Bull., 30: 1042-1047, 2007.
[Abstract]
14) Saitoh Y., Koizumi K., Sakurai H., Minami T., and Saiki I.:
RANKL-induced down-regulation of CX3CR1 via PI3K/Akt signaling pathway suppresses Fractalkine/CX3CL1-induced cellular responses in RAW264.7 cells.

Biochem. Biophys. Res. Commun., 364: 417-422, 2007.
[Abstract]

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富山大学和漢医薬学総合研究所 病態生化学分野
〒 930-0194 富山市杉谷2630
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