病態生化学分野
分野概要 スタッフ 研究室員 研究内容 研究業績 アルバム  
          

研究業績

≪ 前年 2013年 翌年 ≫

著書、総説

1) Waiwut P, Inoue H, Saiki I, and Sakurai H.:
Gomisin N: A herb-derived compound that enhances death receptor-mediated apoptosis of cancer cells.
Traditional Medicine New Research, (Ed.)Yoshiharu Motoo.nova science Publishers, Inc., New York, pp147-157, 2013.
2)

済木育夫:トピックス第29回和漢医薬学会学術大会 シンポジウム1 「和漢医薬学とがん」、
漢方医薬学雑誌、20(3):15-17,2013

3)

小泉桂一、犬嶌明子、大江未来広、柴原直利、済木育夫:トピックス:漢方薬のワクチンアジュバント効果、最新医学、68 (4): 869-873, 2013.

4)

済木育夫:漢方薬とがん転移、日本統合医療学会誌、6 (1): 60-65, 2013.

5) 済木育夫:漢方薬によるがん転移抑制とそのメカニズム、日本女性医学学会ニューズレター、18(3):5, 2013. 
6) 横山悟:特集:次世代シグナル伝達研究―先駆的基礎解析と臨床・創薬への展開―,悪性黒色腫におけるシグナル伝達,生化学 第85巻 第6号,469-474,2013
7) 早川芳弘:特集:腫瘍免疫学とがん免疫療法、第1章 腫瘍免疫における免疫担当細胞と免疫分子の役割、5. NK細胞およびNKT細胞の腫瘍免疫応答における役割、実験医学、31(12増刊),59-65,2013

原著論文

1) Jeong D, Watari K, Shirouzu T, Ono M, Koizumi K, Saiki I, Kim YC, Tanaka C, Higuchi R, Miyamoto T.:
Studies on lymphangiogenesis inhibitors from Korean and Japanese crude drugs.
Biol Pharm Bull., 36(1), 152-157, 2013.[Abstract]
2) Kee JY, Arita Y, Shinohara K, Ohashi Y, Sakurai H, Saiki I, Koizumi K.:
Antitumor immune activity by chemokine CX3CL1 in an orthotopic implantation of lung cancer model in vivo.
Mol Clin Oncol., 1,35-40, 2013.
3) Kee JY, Ito A, Hojo S, Hashimoto I, Igarashi Y, Tsukada K, Irimura T, Shibahara N, Nakayama T, Yoshie O, Sakurai H, Saiki I, Koizumi K.:
Chemokine CXCL16 suppresses liver metastasis of colorectal cancer via augmentation of tumor-infiltrating natural killer T cells in a murine model.
Oncol Rep., 29(3), 975-982, 2013. [Abstract]
4) Xue R, Han N, Sakurai H, Saiki I, Ye C, Yin J.:
Cytotoxic Cardiac Glycosides from the Roots of Streptocaulon juventas.
Planta Med., 79(2),157-162, 2013. [Abstract]
5) Abdelhamed S, Yokoyama S, Hafiyani L, Kalauni SK, Hayakawa Y, Awale S, Saiki I.:
Identification of plant extracts sensitizing breast cancer cells to TRAIL.
Oncol Rep., 29(5),1991-1998, 2013. [Abstract]
6) Haq R, Yokoyama S, Hawryluk EB, Jonsson GB, Frederick DT, McHenry K, Porter D, Tran TN, Love KT, Langer R, Anderson DG, Garraway LA, Duncan LM, Morton DL, Hoon DS, Wargo JA, Song JS, Fisher DE.:
BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition.
Proc Natl Acad Sci U S A., 110(11), 4321-4326, 2013. [Abstract]
7) Haq R, Shoag J, Andreu-Perez P, Yokoyama S, Edelman H, Rowe GC, Frederick DT, Hurley AD, Nellore A, Kung AL, Wargo JA, Song JS, Fisher DE, Arany Z, Widlund HR.:
Oncogenic BRAF Regulates Oxidative Metabolism via PGC1αand MITF.
Cancer Cell.
, 23(3), 302-315, 2013. [Abstract]
8) Takahashi K, Takeda K, Saiki I, Irimura T, Hayakawa Y.:
Functional roles of tumor necrosis factor-related apoptosis-inducing ligand-DR5 interaction in B16F10 cells by activating the nuclear factor-κB pathway to induce metastatic potential.
Cancer Sci., 104:558-562, 2013.[Abstract]
Takahashi K, Takeda K, Saiki I, Irimura T, Hayakawa Y.:
RAIL-DR5 interaction by NFk B pathway induces matastartic potential.Lung metastasis of intravenously inoculated B16F10 mouse melanoma cells stimulated witaout (left panels) or with TRAIL(right panels) was visualized by bioluminescent imaging in mice.
Canceer Sci., 104(5), Cover, 2013.
9) Lirdprapamongkol K, Sakurai H, Abdelhamed S, Yokoyama S, Athikomkulchai S, Viriyaroj A, Awale S, Ruchirawat S, Svasti J, Saiki I.:
Chrysin overcomos TRAIL resistance of cancer cells though Mcl-1 down-regulation by inhibiting STAT3 phoshorylation.
Int.J.Oncol., 43:329-337, 2013. [Abstract]
10) Refaat A, Abdelhamed S, Yagita H, Inoue H, Yokoyama S, Hayakawa Y Saiki I.:
Berberine enhances TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-mediated apoptosis in breast cancer.
Oncol.Letts., 6(3),840-844, 2013. [Abstract]
11) Shirouzu T, Watari K, Ono M, Koizumi K, Saiki I, Tanaka C,van Soest RW,Miyamoto T.:
Structure,Synthesis,and Biological Activity of a C-20 Bisacetylenic Alcohol from a Marine Sponge Callyspongia sp.
J.Nat.Prod. , 76(7), 1337-1342, 2013. [Abstract]
12) Jiang Y-L, Miyanaga S, Han X-Z, Tang L-Q, Igarashi Y, Saiki I, Liu Z-P.:
Synthesis and structure-activity relationships studies of brertemicin analogues as anti-invasive agents.
J.Antibiot., 66(9), 531-537, 2013. [Abstract]
13) Sato K, Shin M-S, Sakimura A, Kwanishi M, Zhou Y, Tanaka T, Yokoyama S, Koizumi K, Saiki I, Sakurai H.:
Inverse correlatio between threonine-669 phosphorylation and constitutive tyrosine phosphorylation in the asymmetric EGFR dimmer conformation.
Cancer Sci., 104(10), 1315-1322, 2013. [Abstract]
14) Alves C.P, Moraes M.H, Sousa J.F, Pontes C.L, Ramao A, Yokoyama S, Trindade D.M, Fisher D.E,Espreafico E M.:
Myosin-Vα Contributes to Manifestation of Malignant-Ralated Properties in Melanoma Cells.
J.Invest.Dermatol., 133(12), 2809-2812, 2013. [Abstract]
15) Lirdprapamongkol K, Sakurai H, Abdelhamed S, Yokoyama S, Maruyama T, Athikomkulchai S, Viriyaroj A, Awale S, Yagita H, Ruchirawat S, Svasti J, Saiki I.:
A flavonoid chrysin suppresses hypoxic survival and metastatic growth of mouse breast cancer cells.
Oncol.Rep., 30(5), 2357-2364, 2013. [Abstract]
16) Li P, Furusawa Y, Wei Z-L, Sakurai H, Tabuchi Y, Zhao Q-L, Saiki I, Kondo T.:
TAK1 promotes cell survival by TNFAIP3 and IL-8 dependent and NF-kB independent pathway in HeLa cells exposed to heat stress.
Int.J.Hypertherm., 29(7), 688-695, 2013. [Abstract]
17) Akubar-Bahar M, Andoh T, Ogura K,Hayakawa Y, Saiki I, Kuraishi Y.:
Herbel medicine goshajinkigan prevents paclitaxel-induced mechanical allodynia without impairing anti-tumor activity of paclitaxel.
Evid.Based Complement Alternat.Med. , ID849754, 2013. [Abstract]
18) Kin R, Kato S, Kaneto N, Sakurai H, Hayakawa Y, Li Feng, Tanaka K, Saiki I,Yokoyama S.:
Procyanidin C1 from Cinnamomi Cortex inhibits TGF-β-induced epithelial-to-mesenchymal transition in A549 lung cancer cell lines.
Int.J.Oncol., 43: 1901-1906, 2013. [Abstract]
19) Li F, Tanaka K, Watanabe S, Tezuka Y, Saiki I.:
Dipasperoside A,a novel pyridine alkaloid-coupled iridoid glucoside from the Roots of Dipsacus asper.
Chem.Pharm.Bull., 61(12):1318-1322, 2013. [Abstract]
20) Saiki I, Koizimi K, Goto H, Inujimas A, Namiki T, Raimura M, Kogure T,Tatsumi T,Inoue H,Sakai S,Oka H,Fujimoto M,Hikiami H,Sakurai H,Shibahara N,Shimada Y, Origasa H.:
The long-term effects of a Kampo medicine,Juzentaihoto,on maintenance of antibody titer in elderly people after influenza vaccination.
Evid.Based Complement Alternat.Med., ID568074, 2013. [Abstract]
21) Hang P.T.N., Diep T.T., Dong N.T., Thanh P. V., Saiki I.:
Andrographis paniculata (Burm.f) Nees enhances cytotoxicity in combination with TRAIL and suppresses invasion and migration in MDA MB-231 cell line in vivo.
J.Med.Materials-Hanoi., N6, 355-360, 2013 [Abstract]

ページトップへ戻る

 
トップページ 和漢薬とがん研究の接点を求めて
富山大学和漢医薬学総合研究所 病態生化学分野
〒 930-0194 富山市杉谷2630
TEL 076-434-7620

薬学部生・大学院生募集
English
トップページ 富山大学 和漢研