Division of Pathogenic Biochemistry
Staff Research Publication  

List of Publications

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Books and Reviews

Original Papers

1) Kee J-Y., Inujima A., Andoh T., Tanaka K., Li F., Kuraishi Y., Sakurai H., Shibahara N., Saiki I., Koizumi K.:
Inhibitory effect of Moutan cortex aqueous fraction on mast cell-mediated allergic inflammation.
J. Nat. Med., 69(2), 209-217, 2015.[Abstract]
2) Ajdzanovic V., Medigovic I., Zivanovic J., Mojic M., Milosevic V.:
Membrane steroid receptor-mediated action of soy isoflavones:Tip of the iceberg.

J. Membr. Biol.
, 248(1), 1-6, 2015.[Abstract]
3) Muhammad J.S., Zaidi S.F., Shaharyar S., Refaat A., Usmanghani K., Saiki I., Sugiyama T.:
Anti-inflammatory effect of cinnamaldehyde in Helicobacter pylori induced gastric inflammation.
Biol. Pharm. Bull., 38(1), 109-115, 2015.[Abstract]
4) Xue R., Han N., Xia M., Ye C., Hao Z., Wang L., Wang Y., Yang J., Saiki I., Yin J.:
TXA9, a cardiac glycoside from Streptocaulon juventas, exerts a potent anti-tumor activity against human non-small cell lung cancer cells in vitro and in vivo.
Steroids., 94, 51-59, 2015.[Abstract]
5) Lou C., Yokoyama S., Saiki I., Hayakawa Y.:
Selective anti-cancer activity of Hirsutine against HER2 positive breast cancer cells by inducing DNA damage.
Oncol. Rep., 33(4), 2072-2076, 2015.[Abstract]
6) Toge M., Yokoyama S., Kato S., Sakurai H., Senda K., Doki Y., Hayakawa Y., Yoshimura N., Saiki I.:
Critical contribution of MCL-1 in EMT-associated chemo-resistance in A549 non-small-cell lung cancer.
Int J. Oncol., 46(4), 1844-1848, 2015.[Abstract]
7) Gao F., Yokoyama S., Fujimoto M., Tsuneyama K., Saiki I., Shimada Y., Hayakawa Y.:
Effect of keishibukuryogan on genetic and dietary obesity models.
Evid. Based Complement Alternat. Med., volume 2015 (2015), Article ID 801291.[Abstract]
8) Refaat A., Aminullah, Zhou Y., Kawanishi M., Tomaru R., Abdelhamed S., Shin M-S, Koizumi K., Yokoyama Y., Saiki I., Sakurai H.:
Role of tyrosine kinase-independent phosphorylation of EGFR with activating mutation in cisplatin-treated lung cancer cells.
Biochem. Biophys. Res. Commun., 458, 856-861, 2015.[Abstract]
9) Zaidi S.F., Refaat A., Shin M-S., Zhou Y., Muhammad J.S., Saiki I., Sakurai H., Sugiyama T.:
Helicobacter pylori induces serine/threonine phosphorylation of EGFR via p38/ERK activation in gastric epithelial cells in HB-EGF-independent manner.
Helicobacter., doi: 10.1111/hel.12215., 2015.[Abstract]
10) Inujima A., Yamada M., Takeno N., Hoshina A., Oe M., Shinohara M., Shibahara N., Sakurai H., Saiki I., Koizumi K.:
An herbal plant derived compound, 1,2,3,4,6-penta-O-galloyl-β-D- glucose (PGG), increases cross-presentation of antigens to MHC class I molecules in dendritic cells.
Trad. Kampo Med., 23 FEB 2015 doi:10.1002/tkm2.1017.[Abstract]
11) Wada A., Ito A., itsuka H., Tsuneyama K., Miyazono T., Murakami J., Shibahara N., Sakurai H., Saiki I., Nakayama T., Yoshie O., Koizumi K., Sugiyama T.:
Role of chemokine CX3CL1 in progression of multiple myeloma via CX3CR1 in bone microenvironments.

Oncol. Rep.
, 33(6),2935-2939, 2015.[Abstract]
12) Refaat A., Abdelhamed S., Saiki I., Sakurai H.:
Inhibition of p38 MAPK potentiates the apoptotic effect of berberine/TRAIL combination.
Oncol. Lett., 10,1907-1911,2015.[Abstract]
13) Gao F., Yokoyama S., Fujimoto M., Tsuneyama K., Saiki I., Shimada Y., Hayakawa Y.:
Comparative of two Kampo medicines in a diet-induced mouse obesity model.
Trad. Kampo Med., 13 MAY 2015 doi:10.1002/tkm2.1021.[Abstract]
14) Takahashi K., Nagai N., Tsuneyama K., Saiki I., Irimura T., Hayakawa Y.:
Mammary tissue microenvironment determines T cell-dependent breast cancer-associated inflammation.
Cancer Sci., 106(7),867-874,2015.[Abstract]
15) Eshima S., Yokoyama S., Abe T., Hayakawa Y., Saiki I.:
Multi-pathway cellular analysis on crude natural drugs/herbs from Japanese Kampo formulations
PLoS ONE, 2015 Jun 2;10(6):e0128872.doi:10.1371/journal.pone.0128872.[Abstract]
16) Mudjupa C., Abdelhamed S., Refaat A., Yokoyama S., Saiki I., Vajragupta O.:
Lead compound bearing caffeic scaffold induces EGFR suppression in solid tumor cancer cells.
J. Applied Biomed., doi:10.1016/j.jab.2015.05.001.[Abstract]
17) Zhou Y., Yamada N., Tanaka T., Hori T., Yokoyama S., Hayakawa Y., Yano S., Fukuoka J., Koizumi K., Saiki I., Sakurai H.:
Crucial roles of RSK in cell motility by catalyzing serine phosphorylation of EphA2.
Nature commun., 2015 Jul 9;6:7679. doi: 10.1038/ncomms8679.[Abstract]
18) Lou C., Yokoyama S., Abdelhamed S., Saiki I., Hayakawa Y.:
Targeting ATM pathway for effective therapy against hirsutine-resistant breast cancer cells.
Oncol. Lett., in press, 2015.[Abstract]
19) Managit C., Sakurai H., Saiki I.:
The ethanolic extract of Thevetia Peruviana flowers enhances TNF-α and TRAIL-induced apoptosis of human cervical cancer cells via intrinsic and extrinsic pathways.
Oncol. Letts., in press, 2015.[Abstract]
20) Takeno N., Inujima A., Shinohara K., Yamada M., Shibahara N., Sakurai H., Saiki I., Koizumi K.:
Immune adjuvant effect of Juzentaihoto, a Japanese traditional herbal medicine, on tumor vaccine therapy in mouse model.
Int J. Oncol.,47(6), 2115-2122, 2015 .[Abstract]

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Division of Pathogenic Biochemistry
Institute of Natural Medicine, University of Toyama
2630 Suginoki, Toyama 930-0194, Japan

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