|
Research outline of our lab.
Our laboratory focuses on two main themes.
Studies on the biosynthesis of bioactive compounds in natural resources such as Japanese crude drugs and Kampo medicines
- Investigation of enzymes involved in the biosynthesis of natural products and analysis of their catalytic mechanism based on X-ray crystal structure
- Engineering of biosynthetic enzymes to generate new compounds
- Production of useful compounds using heterologous expression system
Studies on naturally occurring bioactive substances in natural resources
- Discovery o natural inhibitors for FIH, AspH, Arginases I and II, AChE, etc.
- Discovery of natrual anti-inflammatory anti-cancer agents and synthesis of their derivatives
- Investigation of traditional usage of natrual resources from a point of view of chemistry
- Synthesis of caged indole alkaloids and investigation of their bioactivity
Research Topics
|
RSS2.0