PUBLICATIONS

研究業績

天然物化学領域に所属する教員・研究員・学生が関わった研究成果を掲載しています。

2026

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Journal Article

Redirecting MurD inhibitor preference toward MurD2 through glutamate stereochemical inversion. ↗

Qian Z, Nakashima Y, Dairi T, Morita H.

Bioorg. Med. Chem. 143, 118809 (2026)

Journal Article

New enzymes for biosynthesis of 5-azacytidine; a valuable medicine discovered half a century ago. ↗

Umezawa A, Tsunoda T, Nakashima Y, Wang Y-L, Yoneda T, Maruyama C, Matsuyama T, Miyamoto K, Takazawa R, Shimose A, Hamano Y, Li T-L, Inokuma Y, Uchiyama M, Ogasawara Y, Morita H, Dairi T.

Nat. Catal. (2026)

Journal Article

Structural insights into metal-chelating natural inhibitors of Factor Inhibiting HIF-1α. ↗

Akhsanitaqwim Y, Nakashima Y, Ikumi N, Morita H.

J. Nat. Prod. 89, 2405–2412 (2026)

Journal Article

Structural basis of starter-substrate selectivity governed by a single residue in orcinol synthase. ↗

Nakashima Y, Hnin SYY, Kim S, Byeon H, Vimolmangkang S, Morita H.

Chem. Pharm. Bull. 74, 591–597 (2026)

Journal Article

tRNA-Dependent Chemoenzymatic Transformation of Aminoacyl Pendant Moieties of Streptothricin Antibiotics ↗

Maruyama C, Nakashima Y, Matsuda K, Hamdy SA, Uchiyama S, Goto Y, Mori T, Ogasawara Y, Shin-ya K, Abe I, Dairi T, Suga H, Morita H, Hamano Y.

J. Am. Chem. Soc. 148, 12154–12165 (2026)

Journal Article

Phytochemical Analysis, In Vitro Anti-Inflammatory Activity, and In Silico Molecular Docking of the Essential Oil from Munronia lancifolia ↗

Pham TV, Le AT, My NTD, Luu PV, Nguyen NHT, Morita H, Nguyen HM.

J. Oleo Sci. 75, 271–280 (2026)

Review

Anti-cancer effects of Cordyceps sinensis, C. militaris and C. cicadae and their mechanisms of action ↗

Gunter NV, Ong YS, Lai ZW, Morita H, Chamyuang S, Owatworakit A, Mah SH.

J. Asian Nat. Prod. Res. 28, 285–309 (2026)

Journal Article

Multi-omics dissection of steviol glycoside synthesis reveals haplotype-linked specialization of UGT76G genes in Stevia rebaudiana ↗

Shoji S, Fukushima A, Morinaka H, Takagi H, Nakashima Y, Mori T, Kawamura A, Shi D, Torii K, Iwase A, Takeda-Kamiya N, Toyooka K, Morita H, Hirai M, Sugimoto K, Saito K, Hirai T.

New Phytol. 251, 384–404 (2026)

2025

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Journal Article

Thiazole conjugated amino acid derivatives as potent cytotoxic agents ↗

Le HT, Nguyen NTH, Hong QV, Qian Z, Bui TM, Huynh LN, Hnin SYY, Htoo ZP, Le APT, Tran DQ, Morita H, Bui HTB.

RSC Adv. 15, 26860–26872 (2025)

Journal Article

New cerebrosides and ceramide with other constituents from the aerial parts of Raphidiocystis mannii Hook. f. and their cytotoxic activities ↗

Mba Nguekeu YM, Sonfack Fozeng HD, Chukwuma CI, Hnin SYY, Hoang NN, Njoya EM, Ngouela SA, Tene M, Makhafola TJ, Morita H, Awouafack MD.

J. Nat. Med. 79, 412–421 (2025)

Journal Article

Enhanced Production of Rebaudioside D and Rebaudioside M through V155T Substitution in the Glycosyltransferase UGT91D2 from Stevia rebaudiana ↗

Shoji T, Tanaka Y, Nakashima Y, Mizohata E, Komaki M, Sugawara S, Takaya J, Yonekura-Sakakibara K, Morita H, Saito K, Hirai T.

J. Agric. Food Chem. 73, 2019–2032 (2025)

Journal Article

A new ceramide and other constituents from Crinum ornatum (L.f.) Herb. (Amaryllidaceae) and their chemophenetic significance ↗

Kouvourbe K, Waleguele CC, Mba Nguekeu YM, Temgoua EVN, Matheuda EG, Tsepeupon Matchide MG, Tchuente Tchuenmogne MA, Nanfack ARD, Kodama T, Anthonissen S, Dehaen W, Ngouela SA, Tene M, Morita H, Awouafack MD.

Biochem. Syst. Ecol. 121, 104991 (2025)

Journal Article

A new antibacterial neo-clerodane diterpenoid and other constituents from Chasmanthera dependens Hochst. (Menispermaceae) and their chemotaxonomic significance ↗

Ediah SHN, Matheuda EG, Kefossang BA, Nguekeu YMM, Kodama T, Hnin SYY, Qian Z, Awouafack MD, Tsopmo A, Morita H, Tene M.

Biochem. Syst. Ecol. 118, 104922 (2025)

Journal Article

A new 19(10→9)abeo-euphane triterpenoid with other terpenoid components from Trichilia dregeana leaves and their NO production inhibitory activities in LPS-stimulated RAW264.7 macrophages ↗

Mba Nguekeu YM, Kodama T, Htoo ZP, Matheuda EG, Tsepeupon Matchide MG, Ngouela SA, Tene M, Awouafack MD, Morita H.

Chem. Biodivers. 22, e202401919 (2025)

Review

Natural xanthones as modulators of the Nrf2/ARE signaling pathway and potential gastroprotective agents ↗

Gunter NV, Teh SS, Jantan I, Law KP, Morita H, Mah SH.

Phytother. Res. 39, 1721–1734 (2025)

2024

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Journal Article

Facile synthesis of 1,2-disubstituted benzimidazoles as potent cytotoxic agents ↗

Bui HTB, Htoo ZP, Hong VQ, Le HT, Tran DQ, Hnin SYY, Do KM, Morita H.

Chem. Pharm. Bull. 72, 944–949 (2024)

Journal Article

Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases ↗

Hnin SYY, Nakashima Y, Kodama T, Morita H.

ACS Catal. 14, 11865–11880 (2024)

Journal Article

Five pimarane diterpenoids from Kaempferia champasakensis and their cytotoxic activities ↗

Do KM, Hoshino S, Kodama T, Nguyen HM, Ikumi N, Onaka H, Morita H.

J. Nat. Med. 78, 908–918 (2024)

Journal Article

Two new neo-clerodane diterpenoids from Tinospora cordifolia stems ↗

Hoang NN, Hoshino S, Kodama T, Hoang TX, Onaka H, Morita H.

Phytochem. Lett. 63, 54–59 (2024)

Journal Article

Substrate flexibilities of norbelladine synthase and noroxomaritidine/norcraugsodine reductase for hydroxylated and/or methoxylated aldehydes ↗

Hnin SYY, Nakashima Y, Morita H.

Chem. Pharm. Bull. 72, 507–511 (2024)

Journal Article

Three neo-clerodane diterpenoids from Tinospora cordifolia stems and their arginase inhibitory activities ↗

Hoang NN, Hoshino S, Kodama T, Nakashima Y, Do KM, Thao HX, Ikumi N, Onaka H, Morita H.

Chem. Pharm. Bull. 72, 540–546 (2024)

Journal Article

A new 3,4-seco-isopimarane and three new isopimarane diterpenoids from Kaempferia champasakensis collected from Vietnam and their cytotoxic activities ↗

Do KM, Hoshino S, Kodama T, Nguyen HM, Van SL, Ikumi N, Onaka H, Morita H.

J. Nat. Med. 78, 537–546 (2024)

Journal Article

Antibacterial activity of five Indonesian medicinal plants and the isolation of compounds from Plectranthus scutellarioides ↗

Rakainsa SK, Nisa K, Ito T, Morita H.

J. Appl. Pharm. Sci. 14, 185–192 (2024)

Journal Article

New 19(10→9)abeo-euphane-type triterpenoids from Trichilia dregeana leaves and NO production inhibitory activities

Mba Nguekeu YM, Kodama T, Tsepeupon Matchide MG, Do KM, Nghokeng J, Tabakam GT, Tsuge K, Ngouela SA, Mathieu T, Awouafack MD, Morita H.

Fitoterapia 176, 106001 (2024)

Journal Article

Antibacterial activity, cytotoxicity and chemotaxonomic significance of chemical constituents from Alsophila manniana Hook R.M.Tryon (Cyatheaceae) rhizomes ↗

Tsepeupon Matchide MG, Sonfack Fozeng HD, Tchuente Tchuenmogne MA, Anensong CSD, Koagne W, Anthonissen S, Nguekeu YMM, Do KM, Lee YE, Dehaen W, Morita H, Mathieu T, Ngouela SA, Awouafack MD.

Biochem. Syst. Ecol. 114, 104834 (2024)

Journal Article

Solvent-free strategy for facile synthesis and cytotoxicity evaluation of benzimidazole derivatives ↗

Bui HTB, Do KM, Hong QV, Le HT, Hnin SYY, Tran DQ, Mai HV, Morita H.

Tetrahedron 156, 133940 (2024)

Journal Article

Synthesis and cytotoxicity of quinazolinone-based conjugates ↗

Le HT, Do KM, Nguyen QP, Doan CNM, Nguyen NA, Phan TT, Tran XTC, Ha QTK, Tran DQ, Kodama T, Morita H, Bui HTB.

Chem. Pharm. Bull. 72, 61–67 (2024)

Journal Article

Substrate-dependent alteration in the C- and O-prenylation specificities of Cannabis prenyltransferase ↗

Tanaya R, Kodama T, Maneenet J, Yasuno Y, Nakayama A, Shinada T, Takahashi H, Ito T, Morita H, Awale S, Taura F.

Biol. Pharm. Bull. 47, 449–453 (2024)

Review

Dual engineering of olivetolic acid cyclase and tetraketide synthase for the formation of longer alkyl-chain olivetolic acid analogs and their antibacterial activities ↗

Morita H.

Chem. Pharm. Bull. 72, 1–10 (2024)

Journal Article

Cytotoxic potential of dihydrochalcones from Eriosema glomeratum and their semi-synthetic derivatives ↗

Tabakam GT, Kodama T, Tchuenmogne MAT, Hoang NN, Nomin-Erdene B, Ngouela SA, Tene M, Morita H, Awouafack MD.

Nat. Prod. Res. 38, 186–197 (2024)

Journal Article

Peptide epimerase responsible for D-amino acid introduction in poly-γ-glutamic acid biosynthesis ↗

Kato H, Sakuta M, Tsunoda T, Nakashima Y, Morita H, Ogasawara Y, Dairi T.

Biomacromolecules 25, 349–354 (2024)

2023

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Journal Article

Structure of lasso peptide epimerase MslH reveals metal-dependent acid/base catalytic mechanism ↗

Nakashima Y, Kawakami A, Ogasawara Y, Maeki M, Tokeshi M, Dairi T, Morita H.

Nat. Commun. 14, 4752 (2023)

Journal Article

Phenolic derivatives with anti-acetylcholinesterase inhibitory activity from Galeola nudifolia in Vietnam ↗

Do KM, Nakashima Y, Kodama T, Lee Y, Nguyen HM, Ikumi N, Morita H.

Chem. Biodivers. 20, e202301482 (2023)

Journal Article

Identification of a diarylpentanoid-producing polyketide synthase in the biosynthesis of 2-(2-phenylethyl)chromones in agarwood ↗

Morita H, Lee Y, Shi SP.

J. Nat. Med. 77, 667–676 (2023)

Journal Article

Dryoptkirbioside, a new fructofuranoside glycerol, and other constituents from Dryopteris kirbi Hook et Grav rhizomes ↗

Matchide MG, Hnin SYY, Nguekeu YMM, Matheuda EG, Nghokeng J, Tabakam GT, Djoumbissie RAD, Ngouela SA, Lee Y, Tene M, Morita H, Awouafack MD.

Chem. Biodivers. 20, e202301127 (2023)

Journal Article

Arginase inhibitory activities of guaiane sesquiterpenoids from Curcuma comosa rhizomes ↗

Hoang NN, Kodama T, Nakashima Y, Do KM, Hnin SYY, Lee Y, Prema, Ikumi N, Morita H.

J. Nat. Med. 77, 891–897 (2023)

Review

Phenylphenalenone-type phytoalexins in banana (Musa species): a comprehensive review for new research directions ↗

Krishnamurthy P, Ravikumar MJ, Palanivelu SA, Pothiraj R, Suthanthiram B, Subbaraya U, Morita H.

Phytochem. Rev. 22, 187–210 (2023)

Journal Article

Structural basis for binding of the renal carcinoma target hypoxia-inducible factor 2α to prolyl hydroxylase domain 2

Figg Jr WD, Fiorini G, Chowdhury R, Nakashima Y, Tumber A, McDonough MA, Schofield CJ.

Proteins 91, 1510–1524 (2023)

Journal Article

Novel insights into the antibacterial activities of cannabinoid biosynthetic intermediate, olivetolic acid, and its alkyl-chain derivatives

Lee Y, Kodama T, Morita H.

J. Nat. Med. 77, 298–305 (2023)

Journal Article

Unprecedented seco- and isopimarane diterpenoids from Kaempferia marginata rhizomes and their NO inhibition activities

Do KM, Kodama T, Nguyen HM, Ikumi N, Soeda C, Shiokawa K, Morita H.

Phytochemistry 205, 113510 (2023)

Journal Article

Catalytic potential of Cannabis prenyltransferase to expand cannabinoid scaffold diversity ↗

Tanaya R, Kodama T, Lee YE, Yasuno Y, Shinada T, Takahashi H, Ito T, Morita H, Awale S, Taura F.

Org. Lett. 25, 8601–8605 (2023)

Book Chapter

Xanthohumol: Recent Advances on Resources, Biosynthesis, Bioavailability and Pharmacology ↗

Awouafack MD, Lee YE, Morita H.

In Handbook of Dietary Flavonoids, Xiao J (ed.), Springer International Publishing, Cham, pp. 1–23 (2023)

2022

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Review

Structure, function, and engineering of plant polyketide synthases ↗

Mori T, Nakashima Y, Morita H, Abe I.

Methods Enzymol. 676, 1–48 (2022)

Journal Article

Bio-inspired computational design of lankacidin derivatives for the improvement of antitumor activity ↗

Ayoub AT, Nishiura N, Teshima A, Elrefaiy MA, Muslimin R, Do KM, Kodama T, Lewis CW, Chan G, Morita H, Arakawa K.

Future Med. Chem. 14, 1349–1360 (2022)

Journal Article

Catalytic potential of a fungal indole prenyltransferase toward β-carbolines, harmine and harman, and their prenylation effect on antibacterial activities

Hamdy SA, Kodama T, Nakashima Y, Han X, Morita H.

J. Biosci. Bioeng. 134, 311–317 (2022)

Journal Article

Flavanols from Crinum asiaticum and their anti-inflammatory mechanisms

Do KM, Shin M, Kodama T, Win NN, Prema, Nguyen HM, Hayakawa Y, Morita H.

Planta Med. 88, 913–920 (2022)

Journal Article

Structure-based redesign of Fe(II)/2-oxoglutarate-dependent oxygenase AndA to catalyze spiro-ring formation

Mori T, Nakashima Y, Chen H, Hoshino S, Mitsuhashi T, Abe I.

Chem. Commun. 58, 5510–5513 (2022)

Journal Article

A new sterol from the polypore fungus Ganoderma luteomarginatum and its cytotoxic activities ↗

Htoo ZP, Kodama T, Win NN, Ikumi N, Shiokawa K, Morita H.

Nat. Prod. Commun. 17, 1–6 (2022)

Journal Article

Enzymatic formation of a prenyl β-carboline by using a fungal indole prenyltransferase

Hamdy SA, Kodama T, Nakashima Y, Han X, Matsui T, Morita H.

J. Nat. Med. 76, 873–879 (2022)

Journal Article

Design, synthesis and cytotoxicity evaluation of substituted benzimidazole conjugated 1,3,4-oxadiazoles ↗

Nguyen QP, Hue BTB, Do KM, Quy HTK, De TQ, Quoc NC, Phuong NB, Trang PC, Morita H.

Chem. Pharm. Bull. 70, 448–453 (2022)

Journal Article

Marginols A–H, unprecedented pimarane diterpenoids from Kaempferia marginata and their NO inhibitory activities ↗

Do KM, Kodama T, Shin MK, Nu LHT, Nguyen HM, Dang SV, Shiokawa K, Hayakawa Y, Morita H.

Phytochemistry 196, 113109 (2022)

Journal Article

Identification of a diarylpentanoid-producing plant polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood

Wang X, Gao B, Nakashima Y, Mori T, Zhang Z, Kodama T, Lee Y, Zhang Z, Wong CP, Liu Q, Qi B, Wang J, Li J, Liu X, Abe I, Morita H, Tu P, Shi S.

Nat. Commun. 13, 348 (2022)

Journal Article

Dual engineering of olivetolic acid cyclase and tetraketide synthase to generate longer alkyl-chain olivetolic acid analogs ↗

Lee Y, Nakashima Y, Kodama T, Chen X, Morita H.

Org. Lett. 24, 410–414 (2022)

Journal Article

Chemoenzymatic synthesis, computational investigation, and antitumor activity of monocyclic lankacidin derivatives ↗

Muslimin R, Nishiura N, Teshima A, Do KM, Kodama T, Morita H, Lewis CW, Chan G, Ayoub AT, Arakawa K.

Bioorg. Med. Chem. 53, 116551 (2022)

Journal Article

Divergent synthesis of decahydroquinoline-type poison-frog alkaloids ↗

Takashima K, Okada T, Kato A, Yamasaki Y, Akanuma S, Kubo Y, Hosoya K, Morita H, Ito T, Kodama T, Tanabe G, Toyooka N.

ChemistrySelect 7, e202104533 (2022)

Review

沈香の香り成分の生産に関わる酵素の発見

中嶋優

ファルマシア 58, 1110–1114 (2022)

Review

人工沈香の開発に繋がる「沈香の香り成分生合成」に関わる鍵酵素

森田洋行

におい・かおり環境学会誌 53, 242–253 (2022)

2021

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Journal Article

Total synthesis of decahydroquinoline poison frog alkaloids ent-cis-195A and cis-211A ↗

Okada T, Wu N, Takashima K, Ishimura J, Morita H, Ito T, Kodama T, Yamasaki Y, Akanuma S, Kubo Y, Hosoya K, Tsuneki H, Wada T, Sasaoka T, Shimizu T, Sakai H, Dwoskin L, Hussaini SR, Saporito RA, Toyooka N.

Molecules 26, 7529 (2021)

Journal Article

2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases

Nakashima Y, Brewitz L, Tumber A, Salah E, Schofield CJ.

Nat. Commun. 12, 6478 (2021)

Journal Article

Investigation of HIV-1 viral protein R inhibitory activities of twelve Thai medicinal plants and their commercially available major constituents ↗

Jaisi A, Prema, Madla S, Lee YE, Septama A, Morita H.

Chem. Biodivers. 18, e2100540 (2021)

Journal Article

Efficient one-pot tandem synthesis and cytotoxicity evaluation of 2,3-disubstituted quinazolin-4(3H)-one derivatives ↗

Hue BTB, Do KM, Nguyen HTD, Danh TLD, Tran DQ, Mai HV, Morita H.

Tetrahedron 98, 132426 (2021)

Journal Article

A new monoterpene from the rhizomes of Alpinia galanga and its anti-Vpr activity

Win NN, Kodama T, Htoo ZP, Hnin SYY, Ngwe H, Abe I, Morita H.

Fitoterapia 151, 104870 (2021)

Journal Article

Flavonoids from Woodfordia fruticosa as potential SmltD inhibitors in the alternative biosynthetic pathway of peptidoglycan ↗

Lee YE, Kodama T, Win NN, Ki D, Hoang NN, Wong CP, Lae KZW, Ngwe H, Dairi T, Morita H.

Bioorg. Med. Chem. Lett. 36, 127787 (2021)

Journal Article

Anti-Vpr activities of sesqui- and diterpenoids from the roots and rhizomes of Kaempferia candida ↗

Prema, Kodama T, Nyunt HHW, Ngwe H, Abe I, Morita H.

J. Nat. Med. 75, 489–498 (2021)

Book Chapter

Bioactive Compounds from Medicinal Plants in Myanmar ↗

Win NN, Morita H.

Prog. Chem. Org. Nat. Prod. 114, 135–251 (2021)

Journal Article

A new caffeic acid ester and a new ceramide from the roots of Eriosema glomeratum ↗

Tabakam GT, Kodama T, Donfack ARN, Nguekeu YMM, Nomin-Erdene B, Htoo ZP, Do KM, Ngouela SA, Tene M, Morita H, Awouafack MD.

Phytochem. Lett. 45, 82–87 (2021)

Journal Article

Inhibition of cell-intrinsic NF-κB activity and metastatic abilities of breast cancer by aloe-emodin and emodic-acid isolated from Asphodelus microcarpus ↗

Abdellatef AA, Fathy M, Mohammed AESI, Abu Bakr MS, Ahmed AH, Abbass HS, El-Desoky AH, Morita H, Nikaido T, Hayakawa Y.

J. Nat. Med. 75, 840–853 (2021)

Journal Article

Amide Bond Formation Using 4-Coumarate:CoA Ligase from Arabidopsis thaliana ↗

Mori T, Wanibuchi K, Morita H, Abe I.

Chem. Pharm. Bull. 69, 717–720 (2021)

Journal Article

Shanpanootols G and H, Diterpenoids from the Rhizomes of Kaempferia pulchra Collected in Myanmar and Their Vpr Inhibitory Activities ↗

Win NN, Kodama T, Htoo ZP, Hnin SYY, Ngwe H, Abe I, Morita H.

Chem. Pharm. Bull. 69, 913–917 (2021)

Journal Article

Identification of Ophiocordyceps gracilioides by Its Anti-tumor Effects through Targeting the NFκB-STAT3-IL-6 Inflammatory Pathway ↗

Shin MK, Sasaki F, Ki DW, Win NN, Morita H, Hayakawa Y.

Biol. Pharm. Bull. 44, 686–690 (2021)

Journal Article

Anti-metastatic effects of ergosterol peroxide from the entomopathogenic fungus Ophiocordyceps gracilioides on 4T1 breast cancer cells ↗

Shin MK, Sasaki F, Ki DW, Win NN, Morita H, Hayakawa Y.

J. Nat. Med. 75, 824–832 (2021)

Journal Article

Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat ↗

Figg WD Jr, McDonough MA, Chowdhury R, Nakashima Y, Zhang Z, Holt-Martyn JP, Krajnc A, Schofield CJ.

ChemMedChem 16, 2082–2088 (2021)

Journal Article

Human Oxygenase Variants Employing a Single Protein FeII Ligand Are Catalytically Active ↗

Brasnett A, Pfeffer I, Brewitz L, Chowdhury R, Nakashima Y, Tumber A, McDonough MA, Schofield CJ.

Angew. Chem. Int. Ed. 60, 14657–14663 (2021)

Journal Article

Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases ↗

Brewitz L, Nakashima Y, Tumber A, Salah E, Schofield CJ.

J. Fluor. Chem. 247, 109804 (2021)

Journal Article

New Pregnane Glycosides Isolated from Caralluma hexagona Lavranos as Inhibitors of α-Glucosidase, Pancreatic Lipase, and Advanced Glycation End Products Formation ↗

Choucry MA, Shalabi AA, El Halawany AM, El-Sakhawy FS, Zaiter A, Morita H, Chaimbault P, Abdel-Sattar E.

ACS Omega 6, 18881–18889 (2021)

Journal Article

Chemical constituents, total phenolic content, antioxidant activity and bactericidal effect of Dicliptera verticillate (Acanthaceae) ↗

Mbopi PY, Fozeng HDS, Nguekeu YMM, Bitchagno GTM, Ngantchouko CBN, Awouafack MD, Opatz T, Ngouela SA, Morita H, Tene M.

S. Afr. J. Bot. 142, 216–221 (2021)

Journal Article

Pyrrolactams from Marine Sponge Stylissa massa Collected from Myanmar and Their Anti-Vpr Activities ↗

Win NN, Kodama T, Aye AAA, Lae KZW, Ngwe H, Han NM, Abe I, Morita H.

Chem. Pharm. Bull. 69, 702–705 (2021)

Journal Article

Shanpanootols A–F, diterpenoids from Kaempferia pulchra rhizomes collected in Myanmar and their Vpr inhibitory activities ↗

Win NN, Kodama T, Htoo ZP, Hnin SYY, Ngwe H, Abe I, Morita H.

Fitoterapia 151, 104870 (2021)

2020

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Journal Article

Deciphering the biosynthetic mechanism of pelletierine in Lycopodium alkaloid biosynthesis ↗

Wang J, Zhang ZK, Jiang FF, Qi BW, Ding N, Hnin SYY, Liu X, Li J, Wang X, Tu PF, Abe I, Morita H, Shi SP.

Org. Lett. 22, 8725–8729 (2020)

Journal Article

Anti-Vpr activities of homodrimane sesquiterpenoids and labdane diterpenoids from Globba sherwoodiana rhizomes ↗

Prema, Kodama T, Wong CP, El-Desoky AH, Nyunt HHW, Ngwe H, Abe I, Morita H.

Fitoterapia 146, 104705 (2020)

Journal Article

Chemical constituents of the Vietnamese marine sponges Gelliodes sp. and their cytotoxic activities

Ki D, Kodama T, El-Desoky AH, Wong CP, Nguyen HM, Do KM, Thai QM, Nu LHT, Morita H.

Chem. Biodivers. 17, e2000303 (2020)

Journal Article

Three new quassinoids isolated from Picrasma javanica wood and their anti-Vpr activities ↗

Prema, Wong CP, Nugroho AE, El-Desoky AH, Awouafack MD, Win YY, Ngwe H, Abe I, Morita H.

J. Nat. Med. 74, 571–578 (2020)

Journal Article

Three new steroidal saponins from Aspidistra letreae plants and their cytotoxic activities ↗

Ho DV, Hoang HNT, Vo HQ, Nguyen KV, Pham TV, Le AT, Phan KV, Nguyen HM, Morita H, Nguyen HT.

J. Nat. Med. 74, 591–598 (2020)

Journal Article

Chiro-inositol derivatives from Chisocheton paniculatus showing cytotoxic activity and inhibition of NO production ↗

Nguyen KV, Ho DV, Nguyen HT, Do TT, Phan KV, Morita H, Heinamaki J, Raal A, Nguyen TH.

J. Nat. Prod. 83, 1201–1206 (2020)

Journal Article

Antimelanogenic activity of ocotillol-type saponin from Panax vietnamesis

Nguyen HM, Nguyen HT, Win NN, Wong CP, Huynh KLV, Hoang NN, Do KM, Nguyen TH, Ho DV, Nguyen MD, Morita H.

Chem. Biodivers. 17, e2000037 (2020)

Journal Article

New cytotoxic polyacetylene amides from the Egyptian marine sponge Siphonochalina siphonella ↗

Ki D, El-Desoky AH, Kodama T, Wong CP, Abdel-Ghani M, El-Beih AA, Mizuguchi M, Morita H.

Fitoterapia, 104511 (2020)

Journal Article

Anti-inflammatory activities of isopimara-8(9),15-diene diterpenoids and mode of action of kaempulchraols B–D from Kaempferia pulchra rhizomes ↗

Win NN, Hardianti B, Ngwe H, Hayakawa Y, Morita H.

J. Nat. Med. 74, 487–494 (2020)

Journal Article

New pregnane glycosides from Caralluma hexagona Lavranos and their α-glucosidase and pancreatic lipase inhibitory effects ↗

Shalabi AA, El Halawany AM, Choucry MA, El-Sahkawy FS, Morita H, Ki D, AbdelSattar EA.

Phytochem. Lett. 36, 49–57 (2020)

Journal Article

Anti-inflammatory activities of isopimara-8(14),15-diene diterpenoids and mode of action of kaempulchraols P and Q from Kaempferia pulchra rhizomes ↗

Win NN, Hardianti B, Kasahara S, Ngwe H, Hayakawa Y, Morita H.

Bioorg. Med. Chem. Lett. 30, 126841 (2020)

Journal Article

New cytotoxic polyacetylene alcohols from the Egyptian marine sponge Siphonochalina siphonella ↗

Ki D, El-Desoky AH, Wong CP, Abdel-Ghani M, El-Beih AA, Mizuguchi M, Morita H.

J. Nat. Med. 74, 409–414 (2020)

Book Chapter

Bacterial type III polyketide synthases

Wong CP, Morita H.

Comprehensive Natural Products III: Chemistry and Biology, Vol. 1, pp. 250–265 (2020)

Book Chapter

Prenylated flavonoids

Awouafack MD, Wong CP, Tane P, Morita H.

Handbook of Dietary Phytochemicals, pp. 1–23 (2020)

2019

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Review

How structural subtleties lead to molecular diversity for the type III polyketide synthases ↗

Morita H, Wong CP, Abe I.

J. Biol. Chem. 294, 15121–15136 (2019)

Journal Article

Structural elucidation of tenebrathin: Cytotoxic C5-substituted γ-pyrone with nitroaryl side chain from Streptoalloteichus tenebrarius

Hoshino S, Mitsuhashi T, Kikuchi T, Wong CP, Morita H, Awakawa T, Fujita M, Abe I.

Org. Lett. 21, 2330–2334 (2019)

Journal Article

Three new inositol derivatives from Chisocheton paniculatus ↗

Nguyen HT, Tran LTT, Ho DV, Phan KV, Raal A, Morita H.

Tetrahedron Lett. 60, 1841–1844 (2019)

Journal Article

Amino acid residues recognizing isomeric glutamate substrates in UDP-N-acetylmuramic acid-L-alanine-glutamate synthetases ↗

Feng R, Satoh Y, Morita H, Ogasawara Y, Dairi T.

ACS Chem. Biol. 14, 975–978 (2019)

Journal Article

Anti-melanin deposition activity and active constituents of Jatropha multifida stems ↗

Woo S, Wong CP, Win NN, Lae KZW, Woo B, Elsabbagh SA, Liu QQ, Ngwe H, Morita H.

J. Nat. Med. 73, 805–813 (2019)

Journal Article

Viral protein R inhibitors from Swertia chirata of Myanmar ↗

Woo S, Win NN, Oo WMN, Ngwe H, Ito T, Abe I, Morita H.

J. Biosci. Bioeng. 128, 445–449 (2019)

Journal Article

Facile sodium metabisulfite mediated synthesis of 1,2-disubstituted benzimidazoles and cytotoxicity evaluation ↗

Hue BTB, Nguyen HM, Hieu MV, Thanh DLD, Son NH, De TQ, Morita H.

Heterocycles 98, 650–665 (2019)

Journal Article

Two new quassinoids and other constituents from Picrasma javanica wood and their biological activities ↗

Prema, Wong CP, Nugroho AE, Awouafack MD, Win YY, Win NN, Ngwe H, Morita H.

J. Nat. Med. 73, 589–596 (2019)

Journal Article

Bis-iridoid and iridoid glycosides: Viral protein R inhibitors from Picrorhiza kurroa collected in Myanmar

Win NN, Kodama T, Lae KZW, Win YY, Ngwe H, Abe I, Morita H.

Fitoterapia 134, 101–107 (2019)

Journal Article

Lignans with melanogenesis effects from Premna serratifolia wood ↗

Woo S, Hoshino S, Wong CP, Win NN, Awouafack MD, Prema, Ngwe H, Zhang H, Hayashi F, Abe I, Morita H.

Fitoterapia 133, 35–42 (2019)

Journal Article

Dinorcassane diterpenoid from Boesenbergia rotunda rhizomes collected in Lower Myanmar ↗

Win NN, Kyaw MM, Prema, Ngwe H, Ito T, Asakawa Y, Okamoto Y, Tanaka M, Abe I, Morita H.

Chem. Biodivers. 16, e1800657 (2019)

Journal Article

A new tetrahydrofuran type lignan from Premna integrifolia wood ↗

Woo S, Wong CP, Win NN, Hoshino S, Prema, Ngwe H, Abe I, Morita H.

Nat. Prod. Commun. 14, 113–116 (2019)

Journal Article

Brominated diphenyl ethers including a new tribromoiododiphenyl ether from a Vietnamese marine sponge Arenosclera sp. and their antibacterial activities ↗

Ki D, Awouafack MD, Wong CP, Nguyen HM, Thai QM, Nu LHT, Morita H.

Chem. Biodivers. 16, e1800593 (2019)

Journal Article

Synthesis and olfactory properties of Phantolide analogues in racemic and optically active forms ↗

Kawasaki M, Kuroyanagi S, Ito T, Morita H, Tanaka Y, Toyooka N.

Flavour Fragr. J. 34, 113–123 (2019)

Journal Article

A new alkylbenzoquinone from Embelia rowlandii Gilg. (Myrsinaceae) ↗

Bouzeko Tchomtchoua IL, Ndontsa BL, Nguekeu Mba YM, Awouafack MD, Wong CP, Mpetga Simo JD, Mbouangouere R, Tane P, Morita H.

Nat. Prod. Res. 33, 1909–1915 (2019)

Journal Article

A new sterol from the Vietnamese marine sponge Xestospongia testudinaria and its biological activities ↗

Nguyen HM, Ito T, Win NN, Vo HQ, Nguyen HT, Morita H.

Nat. Prod. Res. 33, 1175–1181 (2019)

2018

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Journal Article

Catenulobactins A and B, heterocyclic peptides from culturing Catenuloplanes sp. with mycolic acid-containing bacterium ↗

Hoshino S, Ozeki M, Awakawa T, Morita H, Onaka H, Abe I.

J. Nat. Prod. 81, 2106–2110 (2018)

Journal Article

Pogostemins A–C, three new cytotoxic meroterpenoids from Pogostemon auricularius

Nguyen HT, Tran LTT, Ho DV, Le DV, Raal A, Morita H.

Fitoterapia 130, 100–104 (2018)

Journal Article

Huperphlegmines A and B, two novel Lycopodium alkaloids with an unprecedented skeleton from Huperzia phlegmaria and their acetylcholinesterase inhibitory activities ↗

Nguyen HT, Doan HT, Ho DV, Pham KT, Raal A, Morita H.

Fitoterapia 129, 267–271 (2018)

Journal Article

Tetrahydrofuran lignans: Melanogenesis inhibitors from Premna integrifolia wood collected in Myanmar ↗

Win NN, Woo S, Ngwe H, Prema, Wong CP, Ito T, Okamoto Y, Tanaka M, Imagawa H, Asakawa Y, Abe I, Morita H.

Fitoterapia 127, 308–313 (2018)

Journal Article

Three new abietane-type diterpenoids from the leaves of Indonesian Plectranthus scutellarioides ↗

Ito T, Rakainsa SK, Nisa K, Morita H.

Fitoterapia 127, 146–150 (2018)

Journal Article

A new coumaronochromone and a new alkanoyl-dihydrofuranoflavone glycoside from Eriosema robustum (Fabaceae) ↗

Awouafack MD, Wong CP, Tane P, Morita H.

Phytochem. Lett. 27, 20–24 (2018)

Journal Article

Mirilactams C–E, novel polycyclic macrolactams isolated from combined-culture of Actinosynnema mirum NBRC 14064 and mycolic acid-containing bacterium ↗

Hoshino S, Ozeki M, Wong CP, Zhang H, Hayashi F, Awakawa T, Morita H, Onaka H, Abe I.

Chem. Pharm. Bull. 66, 660–667 (2018)

Journal Article

Antimicrobial and antioxidant activities of triterpenoid and phenolic derivatives from two Cameroonian Melastomataceae plants: Dissotis senegambiensis and Amphiblemma monticola ↗

Nzogong RT, Ndjateu FST, Ekom SE, Fosso JAM, Awouafack MD, Tene M, Tane P, Morita H, Choudhary MI, Tamokou JDD.

BMC Complement. Altern. Med. 18, 159 (2018)

Journal Article

Tricalycoside, a new cerebroside from Tricalysia coriacea (Rubiaceae) ↗

Awouafack MD, Tane P, Morita H.

Chem. Biodivers. 15, e1700472 (2018)

Journal Article

Two new pyrrolo-2-aminoimidazoles from a Myanmarese marine sponge, Clathria prolifera ↗

Woo S, Win NN, Wong CP, Ito T, Hoshino S, Ngwe H, Aye AA, Han NM, Zhang H, Hayashi F, Abe I, Morita H.

J. Nat. Med. 72, 803–807 (2018)

Journal Article

Three new sesquiterpene aminoquinones from Vietnamese Spongia sp. and their biological activities

Ito T, Nguyen HM, Win NN, Vo HQ, Nguyen HT, Morita H.

J. Nat. Med. 72, 298–303 (2018)

Journal Article

A new limonoid from Chisocheton paniculatus fruit collected in Vietnam and its NO production inhibitory activity ↗

Nguyen HT, Ho DV, Raal A, Morita H.

Nat. Prod. Commun. 13, 1255–1257 (2018)

2017

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Journal Article

Three new abietane-type diterpenoids from Plectranthus africanus and their antibacterial activities ↗

Nzogong RT, Nganou BK, Tedonkeu AT, Awouafack MD, Tene M, Ito T, Tane P, Morita H.

Planta Med. 84, 59–64 (2017)

Journal Article

2-Alkylquinolone alkaloid biosynthesis in the medicinal plant Evodia rutaecarpa involves collaboration of two novel type III polyketide synthases ↗

Matsui T, Kodama T, Mori T, Tadakoshi T, Noguchi H, Abe I, Morita H.

J. Biol. Chem. 292, 9117–9135 (2017)

Journal Article

Cycloartane-type triterpene glycosides anopanins A–C with monoacyldigalactosylglycerols from Anodendron paniculatum ↗

Ho VD, Hoang TNH, Vo QH, Phan VK, Le TA, Pham VT, Nguyen MH, Kodama T, Ito T, Morita H.

Phytochemistry 144, 113–118 (2017)

Journal Article

Labdane diterpenoids from Curcuma amada rhizomes collected in Myanmar and their antiproliferative activities ↗

Win NN, Ito T, Ngwe H, Win YY, Prema, Okamoto Y, Tanaka M, Asakawa Y, Abe I, Morita H.

Fitoterapia 122, 34–39 (2017)

Journal Article

New merosesquiterpenes from a Vietnamese marine sponge of Spongia sp. and their biological activities ↗

Nguyen HM, Ito T, Kurimoto S, Ogawa M, Win NN, Hung VQ, Nguyen HT, Kubota T, Kobayashi J, Morita H.

Bioorg. Med. Chem. Lett. 27, 3043–3047 (2017)

Journal Article

Syntheses of benzophenone-xanthone hybrid polyketides and their antibacterial activities ↗

Kodama T, Ito T, Dibwe DF, Woo SY, Morita H.

Bioorg. Med. Chem. Lett. 27, 2397–2400 (2017)

Journal Article

Filamenting temperature-sensitive mutant Z inhibitors from Glycyrrhiza glabra and their inhibitory mode of action ↗

Matsui T, Lallo S, Nisa K, Morita H.

Bioorg. Med. Chem. Lett. 27, 1420–1424 (2017)

Journal Article

New phloroglucinol derivatives from Indonesian Baeckea frutescens ↗

Ito T, Nisa K, Rakainsa SK, Lallo S, Morita H.

Tetrahedron 73, 1177–1181 (2017)

Journal Article

Synthesis and odor properties of Phantolide analogues ↗

Kawasaki M, Kuroyanagi S, Ito T, Morita H, Tanaka Y, Toyooka N.

Tetrahedron 73, 2089–2099 (2017)

Review

Naturally occurring Vpr inhibitors from medicinal plants of Myanmar ↗

Win NN, Ngwe H, Abe I, Morita H.

J. Nat. Med. 71, 579–589 (2017)

Journal Article

A new benzophenanthridine alkaloid from Caloncoba glauca

Agbo JBPAA, Mpetga JDS, Tchuenguem RT, Tsafack RBN, Awouafack MD, Dzoyem JP, Ito T, Bikanga R, Morita H, Tane P.

Nat. Prod. Commun. 12, 367–368 (2017)

Journal Article

Anti-influenza virus activity of extracts from stems of Jatropha multifida Linn. collected in Myanmar ↗

Shoji M, Woo SY, Masuda A, Win NN, Ngwe H, Takahashi E, Kido H, Morita H, Ito T, Kuzuhara T.

BMC Complement. Altern. Med. 17, 96 (2017)

Journal Article

A kaempferol triglycoside from Tephrosia preussii Taub. (Fabaceae) ↗

Mba Nguekeu YM, Awouafack MD, Tane P, Nguedia Lando MR, Kodama T, Morita H.

Nat. Prod. Res. (2017)

Journal Article

Antibacterial activities of chemical constituents from the aerial parts of Hedyotis pilulifera ↗

Nguyen HT, Ho DV, Vo HQ, Le AT, Nguyen HM, Kodama T, Ito T, Morita H, Raal A.

Pharm. Biol. 55, 787–791 (2017)

Book Chapter

Isolation and structure characterization of flavonoids

Awouafack MD, Tane P, Morita H.

Flavonoids—From Biosynthesis to Human Health (2017)

2016

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Journal Article

Manipulation of prenylation reactions by structure-based engineering of bacterial indolactam prenyltransferases ↗

Mori T, Zhang L, Awakawa T, Hoshino S, Okada M, Morita H, Abe I.

Nat. Commun. 7, 10849 (2016)

Journal Article

Structural insight into the enzymatic formation of bacterial stilbene ↗

Mori T, Shimomura K, Saito Y, Yang D, Awakawa T, Morita H, Abe I.

Cell Chem. Biol. 23, 1468–1479 (2016)

Journal Article

A novel class of plant type III polyketide synthase involved in orsellinic acid biosynthesis from Rhododendron dauricum ↗

Taura F, Iijima M, Yamanaka E, Takahashi H, Kenmoku H, Saeki H, Morimoto S, Asakawa Y, Kurosaki F, Morita H.

Front. Plant Sci. 7, 1452 (2016)

Journal Article

Quassinoids: Viral protein R inhibitors from Picrasma javanica bark collected in Myanmar ↗

Win NN, Ito T, Ngwe H, Abe I, Morita H.

Bioorg. Med. Chem. Lett. 26, 4620–4624 (2016)

Journal Article

New antibacterial sesquiterpene aminoquinones from a Vietnamese marine sponge of Spongia sp. ↗

Hien NM, Ito T, Win NN, Kodama T, Hung VQ, Hoai NT, Morita H.

Phytochem. Lett. 17, 288–292 (2016)

Journal Article

New sesquiterpene lactones, vernonilides A and B, from the seeds of Vernonia anthelmintica in Uyghur and their antiproliferative activities ↗

Ito T, Aimaiti S, Win NN, Kodama T, Morita H.

Bioorg. Med. Chem. Lett. 26, 3608–3611 (2016)

Journal Article

Two new cyclopentenones and a new furanone from Baeckea frutescens and their cytotoxicities ↗

Ito T, Nisa K, Kodama T, Tanaka M, Okamoto Y, Ismail, Morita H.

Fitoterapia 112, 321–324 (2016)

Journal Article

A new alkenylmethylresorcinol from the fruits of Ardisia kivuensis

Nguekeu YMM, Ndontsa BL, Mbouangouere R, Awouafack MD, Ito T, Tane P, Morita H.

Nat. Prod. Commun. 11, 661–662 (2016)

Journal Article

Isopimarane diterpenoids from Kaempferia pulchra rhizomes collected in Myanmar and their Vpr inhibitory activity ↗

Win NN, Ito T, Matsui T, Aimaiti S, Kodama T, Ngwe H, Okamoto Y, Tanaka M, Asakawa Y, Abe I, Morita H.

Bioorg. Med. Chem. Lett. 26, 1789–1793 (2016)

Journal Article

A new isoflavanol from the fruits of Kotschya strigosa (Fabaceae) ↗

Awouafack MD, Tchuenguem RT, Ito T, Dzoyem JP, Tane P, Morita H.

Helv. Chim. Acta 99, 321–324 (2016)

Journal Article

Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa ↗

Yang X, Matsui T, Kodama T, Mori T, Zhou X, Taura F, Noguchi H, Abe I, Morita H.

FEBS J. 283, 1088–1106 (2016)

Journal Article

A new iridoid from aerial parts of Hedyotis pilulifera

Hoai NT, Duc HV, Phu NDQ, Kodama T, Ito T, Morita H.

Nat. Prod. Commun. 11, 365–367 (2016)

Journal Article

A new cycloartane-type triterpene and a new eicosanoic acid ester from fruits of Paullinia pinnata L. ↗

Awouafack MD, Ito T, Tane P, Kodama T, Tanaka M, Asakawa Y, Morita H.

Phytochem. Lett. 15, 220–224 (2016)

Journal Article

New cytotoxic phloroglucinols, baeckenones D–F, from the leaves of Indonesian Baeckea frutescens

Nisa K, Ito T, Kodama T, Tanaka M, Okamoto Y, Asakawa Y, Imagawa H, Morita H.

Fitoterapia 108, 20–25 (2016)

Journal Article

Clerodendrumol, a new triterpenoid from Clerodendrum yaundense Gurke (Lamiaceae)

Awouafack MD, Aimaiti S, Tane P, Morita H.

Helv. Chim. Acta 99, 161–164 (2016)

Journal Article

Picrajavanicins H–M, new quassinoids from Picrasma javanica collected in Myanmar and their antiproliferative activities

Win NN, Ito T, Ismail, Kodama T, Win YY, Tanaka M, Okamoto Y, Imagawa H, Ngwe H, Asakawa Y, Abe I, Morita H.

Tetrahedron 72, 746–752 (2016)

Journal Article

New acylphloroglucinol derivatives from the leaves of Baeckea frutescens ↗

Nisa K, Ito T, Subehan, Matsui T, Kodama T, Morita H.

Phytochem. Lett. 15, 42–45 (2016)

Journal Article

Potent water extracts of Indonesian medicinal plants against PTP1B ↗

Saifudin A, Usia T, Lallo S, Morita H, Tanaka K, Tezuka Y.

Asian Pac. J. Trop. Biomed. 6, 38–43 (2016)

Journal Article

The components from aerial parts of Sarcosperma affinis Gagnep. and their antibacterial activities ↗

Nguyen HT, Ho DV, Vo HQ, Hoang THX, Kodama T, Ito T, Morita H, Raal A.

Cogent Chem. 2, 1254421 (2016)

Journal Article

Two Novel Diphenolic Metabolites from the Inedible Mushroom Thelephora palmata ↗

Nishio A, Mikami H, Imagawa H, Hashimoto T, Tanaka M, Ito T, Iguchi M, Iseki K, Noji M, Umeyama A.

Nat. Prod. Commun. 11, 1147–1149 (2016)

Journal Article

Terpenoids, Flavonoids and Acetogenins from Some Malagasy Plants ↗

Nagashima F, Tabuchi Y, Ito T, Harinantenaina L, Asakawa Y.

Nat. Prod. Commun. 11, 153–157 (2016)

2015

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Journal Article

A peptide ligase and the ribosome cooperate to synthesize the peptide pheganomycin ↗

Noike M, Matsui T, Ooya K, Sasaki I, Ohtaki S, Hamano Y, Maruyama C, Ishikawa J, Satoh Y, Ito H, Morita H, Dairi T.

Nat. Chem. Biol. 11, 71–76 (2015)

Journal Article

Structural basis for the formation of acylalkylpyrones from two β-ketoacyl units by the fungal type III polyketide synthase CsyB ↗

Mori T, Yang D, Matsui T, Hashimoto M, Morita H, Fujii I, Abe I.

J. Biol. Chem. 290, 5214–5225 (2015)

Journal Article

Structural basis for the β-carboline alkaloids production by the microbial homodimeric enzyme McbB

Mori T, Hoshino S, Sahashi S, Wakimoto T, Matsui T, Morita H, Abe I.

Chem. Biol. 22, 898–906 (2015)

Journal Article

Expression, purification, and crystallization of a plant polyketide cyclase from Cannabis sativa ↗

Yang X, Matsui T, Mori T, Taura F, Noguchi H, Abe I, Morita H.

Acta Crystallogr. F 71, 1470–1474 (2015)

Journal Article

Picrajavanicins A–G, quassinoids from Picrasma javanica collected in Myanmar ↗

Win NN, Ito T, Ismail, Kodama T, Win YY, Tanaka M, Ngwe H, Asakawa Y, Abe I, Morita H.

J. Nat. Prod. 78, 3024–3030 (2015)

Journal Article

Kaempulchraols P–T: diterpenoids from the Kaempferia pulchra rhizomes collected in Myanmar

Win NN, Ito T, Aimaiti S, Kodama T, Tanaka M, Ngwe H, Asakawa Y, Abe I, Morita H.

J. Nat. Prod. 78, 2306–2309 (2015)

Journal Article

Kaempulchraols A–H, diterpenoids from the rhizomes of Kaempferia pulchra collected in Myanmar ↗

Win NN, Ito T, Aimaiti S, Imagawa H, Ngwe H, Abe I, Morita H.

J. Nat. Prod. 78, 1113–1118 (2015)

Journal Article

Kaempulchraols I–O: new isopimarane diterpenoids from Kaempferia pulchra rhizomes collected in Myanmar and their antiproliferative activity

Win NN, Ito T, Aimaiti S, Kodama T, Imagawa H, Ngwe H, Asakawa Y, Abe I, Morita H.

Tetrahedron 71, 4707–4713 (2015)

Journal Article

A new polyoxygenated cyclohexene and a new megastigmane glycoside from Uvaria grandiflora ↗

Ho DV, Kodama T, Le HTB, Phan KV, Do TT, Bui TH, Le AT, Win NN, Imagawa H, Ito T, Morita H, Nguyen HT.

Bioorg. Med. Chem. Lett. 25, 3246–3250 (2015)

Journal Article

Anti-austeritic constituents of the Congolese medicinal plant Aframomum melegueta

Dibwe DF, Awale S, Morita H, Tezuka Y.

Nat. Prod. Commun. 10, 997–999 (2015)

Journal Article

Preferential cytotoxic constituents of Andrographis paniculata and their preferential cytotoxicity against human pancreatic cancer cell lines

Lee S, Morita H, Tezuka Y.

Nat. Prod. Commun. 10, 1153–1158 (2015)

Journal Article

Preferential cytotoxicity of crude drugs used in Japanese Kampo medicines against human pancreatic cancer PANC-1 and PSN-1 cells ↗

Lee S, Dibwe DF, Li F, Morita H, Tezuka Y.

Traditional & Kampo Medicine 2, 35–42 (2015)

2014

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Journal Article

Phytochemical investigation of the active constituents from Caesalpinia sappan on stimulation of osteoblastic cells ↗

Subehan, Rifai Y, Mufidah, Ismail, Aswad M, Morita H.

Plant Biotechnol. 31, 505–509 (2014)

Journal Article

A new polyoxygenated cyclohexane and other constituents from Kaempferia rotunda and their cytotoxic activity ↗

Subehan, Lee S, Dibwe DF, Tezuka Y, Morita H.

Nat. Prod. Res. 28, 1754–1759 (2014)

Journal Article

Muchimangins G–J, fully substituted xanthones with a diphenylmethyl substituent, from Securidaca longepedunculata ↗

Dibwe DF, Awale S, Kadota S, Morita H, Tezuka Y.

J. Nat. Prod. 77, 1241–1244 (2014)

Journal Article

Expression, purification, and crystallization of a fungal type III polyketide synthase that produces the csypyrones ↗

Yang D, Mori T, Matsui T, Hashimoto M, Morita H, Fujii I, Abe I.

Acta Crystallogr. F 70, 730–733 (2014)

Journal Article

Two new diphenylmethyl-substituted xanthones from Securidaca longepedunculata ↗

Dibwe DF, Awale S, Kadota S, Morita H, Tezuka Y.

Nat. Prod. Commun. 9, 655–657 (2014)

Journal Article

Muchimangins E and F: novel diphenylmethyl-substituted xanthones from Securidaca longepedunculata ↗

Dibwe DF, Awale S, Kadota S, Morita H, Tezuka Y.

Tetrahedron Lett. 55, 1916–1919 (2014)

2013

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Journal Article

Heptaoxygenated xanthones as anti-austerity agents from Securidaca longepedunculata

Dibwe DF, Awale S, Kadota S, Morita H, Tezuka Y.

Bioorg. Med. Chem. 21, 7663–7668 (2013)

Journal Article

Cloning and structure-function analyses of quinolone- and acridone-producing novel type III polyketide synthases from Citrus microcarpa ↗

Mori T, Shimokawa Y, Matsui T, Kinjo K, Kato R, Noguchi H, Sugio S, Morita H, Abe I.

J. Biol. Chem. 288, 28845–28858 (2013)

2012

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Journal Article

Benzophenone synthase from Garcinia mangostana L. pericarps

Nualkaew N, Morita H, Shimokawa Y, Kinjo K, Kushiro T, De-Eknamkul W, Ebizuka Y, Abe I.

Phytochemistry 77, 60–69 (2012)

Journal Article

Expression, purification and crystallization of an indole prenyltransferase from Aspergillus fumigatus ↗

Chen J, Morita H, Kato R, Noguchi H, Sugio S, Abe I.

Acta Crystallogr. F 68, 355–358 (2012)

Review

Benzalacetone synthase ↗

Shimokawa Y, Morita H, Abe I.

Front. Plant Sci. 3, 57 (2012)

Journal Article

Prenylation of a nonaromatic carbon of indolylbutenone by a fungal indole prenyltransferase ↗

Chen J, Morita H, Wakimoto T, Mori T, Noguchi H, Abe I.

Org. Lett. 14, 3080–3083 (2012)

Journal Article

Damnacanthal from the Congolese medicinal plant Garcinia huillensis has a potent preferential cytotoxicity against human pancreatic cancer PANC-1 cells

Dibwe DF, Awale S, Kadota S, Tezuka Y.

Phytother. Res. (2012)

Journal Article

Anti-austerity agents from Rhizoma et Radix Notopterygii (Qianghuo)

Li F, Okamura Y, Dibwe DF, Awale S, Kadota S, Tezuka Y.

Planta Med. 78, 796–799 (2012)

Journal Article

Protein tyrosine phosphatase 1B inhibitory activity of Indonesian herbal medicines and constituents of Cinnamomum burmannii and Zingiber aromaticum

Saifudin A, Kadota S, Tezuka Y.

J. Nat. Med. (2012)

Journal Article

Protein tyrosine phosphatase 1B (PTP1B)-inhibiting constituents from the leaves of Syzygium polyanthum

Saifudin A, Tanaka K, Kadota S, Tezuka Y.

Planta Med. 78, 1378–1381 (2012)

Journal Article

Structural reorganization of the bacterial cell division protein FtsZ from Staphylococcus aureus

Matsui T, Yamane J, Mogi N, Yamaguchi H, Takemoto H, Yao M, Tanaka I.

Acta Crystallogr. D 68, 1175–1188 (2012)

Journal Article

Molecular cloning and characterization of copper amine oxidase from Huperzia serrata ↗

Sun J, Morita H, Chen G, Noguchi H, Abe I.

Bioorg. Med. Chem. Lett. 22, 5784–5790 (2012)

Review

Engineering of plant type III polyketide synthases ↗

Wakimoto T, Morita H, Abe I.

Methods Enzymol. 515, 337–358 (2012)