Hayakawa Yoshihiro Professor
Hayakawa Yoshihiro
AffiliationSection of Host Defences, Division of Bioscience, Department of Research and Development / Division of International Cooperative Research
Research fieldsImmunology, Cancer biology
Campus careerPhD.
Biography University of Toyama Faculty Research Profiles
Education
1996, March Toyama Medical & Pharmaceutical University, Faculty of Pharmaceutical Sciences
1998, March Toyama Medical & Pharmaceutical University, Graduate School of Pharmaceutical Sciences, MS
2001, March Toyama Medical & Pharmaceutical University, Graduate School of Pharmaceutical Sciences, PhD
Job career
2001, April Toyama Medical & Pharmaceutical University, Institute of Natural Medicine, Postdocoral Fellow
2001, November Peter MacCallum Cancer Centre (Melbourne), Cancer Immunology Program, Senior Research Officer
2007, January Merck Research Laboratories (Banyu, Tsukuba Research Institute), Pharmacology Department, Research Fellow (Group Leader)
2009, March The University of Tokyo, Graduate School of Pharmaceutical Sciences, Project Associate Lecturer
2011, March The University of Tokyo, Graduate School of Pharmaceutical Sciences, Project Associate Professor
2012, April University of Toayama, Institute of Natural Medicine, Associatae Professo
2017, April University of Toayama, Institute of Natural Medicine, Professor
Research theme
Department
Division
Section
Project
Outline of the research
Main research topics of Hayakawa Lab
・Study of NK cell biology and its roles in immunity
・Role of innate immune responses in cancer progression
・Immunological study of inflammatory & allergic diseases
・Modulation of immune responses and immunological diseases by Kampo medicines
・Study to regulate cancer progression & metastasis
Thoughts on research
Do, or do not. There is no try.
Paper
He K, Kimura T, Takeda K, Hayakawa Y, Characterization of anti-asialo-GM1 monoclonal antibody. Biochem Biophys Res Commun. 2025 Jan;743:151197.
Shinzawa Y, Sasaki SI, Iwabuchi S, Hashimoto S, Kawada M, Hayakawa Y. Protein phosphatase 2A inhibitor modulates natural killer cell homeostasis in peripheral tissues. Biochem Biophys Res Commun. 2024;741:151020.
He K, Shinzawa Y, Iwabuchi S, Hashimoto S, Sasaki SI, Hayakawa Y, Homeostatic self-MHC-I recognition regulates anti-metastatic function of mature lung natural killer cells. Biochem Biophys Res Commun. 2024;738:150906.
Shinzawa Y, Hara D, Shinguryo Y, Yokoyama S, Kawada M, Hayakawa Y, PP2A negatively regulates NK cell T-bet expression and anti-tumor effector function. Int Immunol. 2024;37(2):97-107.
Ucche S, Yokoyama S, Mojic M, Oki K, Ohshima C, Tsuihiji H, Takasaki I, Tahara H, Hayakawa Y. GSTA4 governs melanoma immune resistance and metastasis. Mol Cancer Res. 2022; 21(1):76-85.
keyword
Cancer, Immunology, Inflammation, metastasis, Host defenses, Natural Killer cell
