Research area

Section of Neuromedical Science, Division of Bioscience Unit

Outline of the research

“Section of Neuromedical Science” including two units progresses researches aiming at overcoming neurodegenerative diseases and age-related diseases from respective viewpoints. Laboratory of Neuromedical Science conducts a wide range of research, from basic research to clinical research, to find epoch-making therapeutic agents for intractable Neurodegenerative diseases and to elucidate the factors controlling disease states. Laboratory of Consilienceology for Wakan-yaku conducts research based on the originality and the theories of Wakan-yaku (Japanese oriental medicines) to discover new therapeutic concepts for functional psychiatric disorders and heart diseases.

Research Projects

Laboratory of Neuromedical Science (Professor Chihiro Tohda; Assist. Prof. Ximeng Yang; Assist. Prof.Yuna Inada)

  1. Elucidation of the molecular mechanism of restoring the neuronal network for homeostasis and/or improvement of neural function.
  2. Traditional medicine research for developing fundamental therapeutic drugs for Alzheimer’s disease, spinal cord injury and sarcopenia.
  3. Molecular basis of crosstalk between the central nervous system and peripheral organs, which controls neural function.
  4. Clinical study aiming to develop new botanical drugs and new usage of Kampo formulas.
  5. Clinical study to analyze factors affecting physical and mental health and to identify biomarkers of well-being.

Laboratory of Consilienceology for Wakan-yaku (Assoc. Prof. Michihisa Tohda)

  1. Providing evidence for Wakan-yaku theories and supplying new research strategies based on it
  2. Elucidation of unique effects of Wakan-yaku closely related on physiological reactions and development of ultra-low concentration therapeutic compounds based on the theories
  3. Novel classification of depression based on the Wakan-yaku theories, elucidation of pathogenic mechanism, and development of new antidepressant drugs
  4. Development of novel Wakan-yaku prescriptions to prevent “heart failure due to the side effects by anti-cancer drugs” and “fatal recurrent myocardial infarction”

Researcher in charge