Department of Clinical Application
Outline of the research
We will promote clinical research aimed to create new application of ethical Kampo formulation and that aimed to develop botanical drug product. Thus, we will promote translational research in collaboration with Center for Clinical Research in University Hospital based on the seeds gained from basic research at Institute of Natural Medicine. In addition, we will feed back questions in the clinical practice to Institute of Natural Medicine and provide a bridge to reverse translational research.
Research Projects
- Clinical trial aimed at new application of ethical Kampo formulation.
- Effect of Hachimijiogan on cognitive function in Alzheimer’s disease patients.
- Effect of Ryokeijutsukanto on Meniere’s disease.
- Effect of Shakuyakukanzoto on paclitaxel-induced myalgia/arthralgia.
- Clinical trial aimed at the development of botanical drug product.
- Effect of Dioscorea batatas extract on cognitive function.
- Effect of Cistanche tubulosa extract on cervical spondylotic myelopathy.
- Effect of Cistanche tubulosa extract on physical activity in chronic obstructive lung disease patients.
Effect of Hachimijiogan extract on cognitive function in Alzheimer’s disease patients based on Alzheimer’s Disease Assessment Scale-cognitive component- Japanese version（ADAS-Jcog）. In the subgroup analysis, the differences in the change from baseline to 3 and 6 months for women were 3.70 (90% Confidence interval (CI),0.50 to 6.91, P=0.059) and 2.90 (90%CI,0.09 to 5.71, P=0.090), respectively. (Kainuma M, et al. Frontiers in Pharmacology. 2022) Keywords
- Clinical trial
- Translational research
- Reverse translational research
- Kampo medicines
- Botanical drug product
Members
- Prof. Mosaburo Kainuma
- Visiting Prof. Eiichi Tahara
- Assoc. Prof. Makoto Fujimoto
- Assist. Prof. Hidetoshi Watari
Researcher in charge
Outline of the research
We will promote clinical research aimed to create new application of ethical Kampo formulation and that aimed to develop botanical drug product. Thus, we will promote translational research in collaboration with Center for Clinical Research in University Hospital based on the seeds gained from basic research at Institute of Natural Medicine. In addition, we will feed back questions in the clinical practice to Institute of Natural Medicine and provide a bridge to reverse translational research.
Research Projects
- Clinical trial aimed at new application of ethical Kampo formulation.
- Effect of Hachimijiogan on cognitive function in Alzheimer’s disease patients.
- Effect of Ryokeijutsukanto on Meniere’s disease.
- Effect of Shakuyakukanzoto on paclitaxel-induced myalgia/arthralgia.
- Clinical trial aimed at the development of botanical drug product.
- Effect of Dioscorea batatas extract on cognitive function.
- Effect of Cistanche tubulosa extract on cervical spondylotic myelopathy.
- Effect of Cistanche tubulosa extract on physical activity in chronic obstructive lung disease patients.
Keywords
- Clinical trial
- Translational research
- Reverse translational research
- Kampo medicines
- Botanical drug product
Members
- Prof. Mosaburo Kainuma
- Visiting Prof. Eiichi Tahara
- Assoc. Prof. Makoto Fujimoto
- Assist. Prof. Hidetoshi Watari
