研究テーマ
部門
分野
領域
プロジェクト
研究の概要
脂質代謝の解析から食品・和漢薬の新機能性を見いだす
研究への想い
万事塞翁が馬
論文
Watanabe S, Fujita K.: Dietary Hyodeoxycholic Acid Exerts Hypolipidemic Effects by Reducing Farnesoid X Receptor Antagonist Bile Acids in Mouse Enterohepatic
Tissues. Lipids, 49:963-973, 2014
Watanabe S., Fujita K., Tsuneyama K., NoseM.: Changes in liver lipidomics associated with sodium cholate-induced liver injury and its prevention by boiogito, a Japanese herbal medicine, in mice. Trad Kampo Med, 3: 9-19, 2015.
Fujita K., Iguchi Y., Une M., Watanabe S.: Ursodeoxycholic acid suppresses lipogenesis in mouse liver: Possible role of the decrease in β-muricholic acid, a farnesoid X receptor antagonist. Lipids 52. 335-344, 2017.
Watanabe S., Fujita K., Nishida T., Imura J.: Ameliorative effect of animal bile preparations on dextran sulfate sodium-induced colitis in mice. Trad Kampo Med, 5: 67-74, 2018.
Watanabe S., Chen Z., Fujita K.: Boiogito prevents dietary lithocholic acid (LCA)-induced cholestatic liver injury through the suppression of intestinal LCA absorption. Trad Kampo Med, 6, 71-78, 2019
キーワード
脂肪酸、胆汁酸